Stephen T.C. Wong

Design and applications of a multimodality image data warehouse framework.

Workflow-enabled distributed component-based information architecture for digital medical imaging enterprises.

A neuroinformatics database system for disease-oriented neuroimaging research.

Towards effective and rewarding data sharing.

A web-based federated neuroinformatics model for surgical planning and clinical research applications in epilepsy.

Cancer classification and prediction using logistic regression with Bayesian gene selection.

DBMap: a space-conscious data visualization and knowledge discovery framework for biomedical data warehouse.

A computerized cellular imaging system for high content analysis in Monastrol suppressor screens.

Multiclass cancer classification by using fuzzy support vector machine and binary decision tree with gene selection.

Parameters selection in gene selection using Gaussian kernel support vector machines by genetic algorithm.

Computerized image analysis for quantitative neuronal phenotyping in zebrafish.

76-space analysis of grey matter diffusivity: methods and applications.

Protein structure similarity from Principle Component Correlation analysis.

Boosting alternating decision trees modeling of disease trait information.

Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss.

Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation.

Bayesian variable selection for gene expression modeling with regulatory motif binding sites in neuroinflammatory events.

Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy.

Automated neurite labeling and analysis in fluorescence microscopy images.

76-space analysis of grey matter diffusivity: methods and applications.

Towards automated cellular image segmentation for RNAi genome-wide screening.

Repulsive force based snake model to segment and track neuronal axons in 3D microscopy image stacks.

A novel tracing algorithm for high throughput imaging Screening of neuron-based assays.

Context based mixture model for cell phase identification in automated fluorescence microscopy.

Automated neurite extraction using dynamic programming for high-throughput screening of neuron-based assays.

Detection of molecular particles in live cells via machine learning.

Characteristic of hypothalamic kisspeptin expression in the pubertal development of precocious female rats.

An automated feedback system with the hybrid model of scoring and classification for solving over-segmentation problems in RNAi high content screening.

Dendritic spine detection using curvilinear structure detector and LDA classifier.

Tracking molecular particles in live cells using fuzzy rule-based system.

Automatic dendritic spine analysis in two-photon laser scanning microscopy images.

Detection of blob objects in microscopic zebrafish images based on gradient vector diffusion.

3D cell nuclei segmentation based on gradient flow tracking.

Brain tissue segmentation based on DTI data.

Automated axon tracking of 3D confocal laser scanning microscopy images using guided probabilistic region merging.

High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles.

Comparison of reversible-jump Markov-chain-Monte-Carlo learning approach with other methods for missing enzyme identification.

Least-square conformal brain mapping with spring energy.

Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy.

ZFIQ: a software package for zebrafish biology.

Cellular phenotype recognition for high-content RNA interference genome-wide screening.

An automated method for cell detection in zebrafish.

Reconstruction of central cortical surface from brain MRI images: method and application.

MR analysis of regional brain volume in adolescent idiopathic scoliosis: neurological manifestation of a systemic disease.

3D Axon structure extraction and analysis in confocal fluorescence microscopy images.

Using nonlinear diffusion and mean shift to detect and connect cross-sections of axons in 3D optical microscopy images.

A quantitative study of factors affecting in vivo bioluminescence imaging.

Workflow and methods of high-content time-lapse analysis for quantifying intracellular calcium signals.

MeCP2, a key contributor to neurological disease, activates and represses transcription.

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.

An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling.

Reversible jump MCMC approach for peak identification for stroke SELDI mass spectrometry using mixture model.

The knowledge-integrated network biomarkers discovery for major adverse cardiac events.

Registration of 3-D CT and 2-D flat images of mouse via affine transformation.

Computational prediction models for early detection of risk of cardiovascular events using mass spectrometry data.

Robust 3D reconstruction and identification of dendritic spines from optical microscopy imaging.

Conditional random pattern algorithm for LOH inference and segmentation.

A novel method for cortical sulcal fundi extraction.

Multiple distinct clones may co-exist in different lineages in myelodysplastic syndromes.

Improved residue function and reduced flow dependence in MR perfusion using least-absolute-deviation regularization.

A screening platform for glioma growth and invasion using bioluminescence imaging. Laboratory investigation.

Introduction to the special issue of "Advances in Molecular Imaging".

A novel cell segmentation method and cell phase identification using Markov model.

Identification of biomarkers for risk stratification of cardiovascular events using genetic algorithm with recursive local floating search.

Pattern-selection based power analysis and discrimination of low- and high-grade myelodysplastic syndromes study using SNP arrays.

An automated pipeline for dendrite spine detection and tracking of 3D optical microscopy neuron images of in vivo mouse models.

Automated brain tumor segmentation using spatial accuracy-weighted hidden Markov Random Field.

生物发光成像显示由阿尔茨海默病中的淀粉样蛋白抑制肿瘤细胞增殖。

Conference Scene: Wake-up call for the engineering and biomedical science communities in nanomedicine.

Multiple nuclei tracking using integer programming for quantitative cancer cell cycle analysis.

A novel peak detection approach with chemical noise removal using short-time FFT for prOTOF MS data.

A hybrid approach to automatic clustering of white matter fibers.

Simultaneous consideration of spatial deformation and tensor orientation in diffusion tensor image registration using local fast marching patterns.

Joint registration and segmentation of serial lung CT images for image-guided lung cancer diagnosis and therapy.

Computational Systems Bioinformatics and Bioimaging for Pathway Analysis and Drug Screening.

A NOVEL SURFACE-BASED GEOMETRIC APPROACH FOR 3D DENDRITIC SPINE DETECTION FROM MULTI-PHOTON EXCITATION MICROSCOPY IMAGES.

Computer-assisted quantitative evaluation of therapeutic responses for lymphoma using serial PET/CT imaging.

A neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons.

Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study.

Online Phenotype Discovery based on Minimum Classification Error Model.

Catch the wave--nanotechnology, the future is now.

A local fast marching-based diffusion tensor image registration algorithm by simultaneously considering spatial deformation and tensor orientation.

Conditional random pattern model for copy number aberration detection.

Cell segmentation using front vector flow guided active contours.

An automatic and robust algorithm of reestablishment of digital dental occlusion.

Reconstruction of the neuromuscular junction connectome.

A computational framework for studying neuron morphology from in vitro high content neuron-based screening.

INTEGRATING MULTI-SCALE BLOB/CURVILINEAR DETECTOR TECHNIQUES AND MULTI-LEVEL SETS FOR AUTOMATED SEGMENTATION OF STEM CELL IMAGES.

An Image Based System Biology Approach for Alzheimer's Disease Pathway Analysis.

Oriented Markov random field based dendritic spine segmentation for fluorescence microscopy images.

Delivery of picosecond lasers in multimode fibers for coherent anti-Stokes Raman scattering imaging.

Cortical and frontal atrophy are associated with cognitive impairment in age-related confluent white-matter lesion.

Semi-supervised drug-protein interaction prediction from heterogeneous biological spaces.

Image-based chemical screening identifies drug efflux inhibitors in lung cancer cells.

Online 4-D CT estimation for patient-specific respiratory motion based on real-time breathing signals.

Motion artifact correction of multi-photon imaging of awake mice models using speed embedded HMM.

Diffusion tensor-based fast marching for modeling human brain connectivity network.

Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients.

A global spatial similarity optimization scheme to track large numbers of dendritic spines in time-lapse confocal microscopy.

MicroRNA-integrated and network-embedded gene selection with diffusion distance.

Multi scale and slice-based approach for automatic spine detection.

Coronary artery segmentation using geometric moments based tracking and snake-driven refinement.

Characterization of a human tumorsphere glioma orthotopic model using magnetic resonance imaging.

The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.

Progress of engineered antibody-targeted molecular imaging for solid tumors (Review).

Label-free high-resolution imaging of prostate glands and cavernous nerves using coherent anti-Stokes Raman scattering microscopy.

Peak tree: a new tool for multiscale hierarchical representation and peak detection of mass spectrometry data.

Coherent anti-Stokes Raman scattering microscopy imaging with suppression of four-wave mixing in optical fibers.

An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data.

Real-time monitoring of cell viability using direct electrical measurement with a patch-clamp microchip.

Use of multimode optical fibers for fiber-based coherent anti-Stokes Raman scattering microendoscopy imaging.

Differential diagnosis of breast cancer using quantitative, label-free and molecular vibrational imaging.

Motion correction for cellular-resolution multi-photon fluorescence microscopy imaging of awake head-restrained mice using speed embedded HMM.

ONLINE THREE-DIMENSIONAL DENDRITIC SPINES MOPHOLOGICAL CLASSIFICATION BASED ON SEMI-SUPERVISED LEARNING.

An Image Driven Systems Biology Approach for Neurodegenerative Disease Studies in the TSC-mTOR Pathway.

On-the-spot lung cancer differential diagnosis by label-free, molecular vibrational imaging and knowledge-based classification.

A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies.

The kinetochore protein Bub1 participates in the DNA damage response.

Aurora-B mediated ATM serine 1403 phosphorylation is required for mitotic ATM activation and the spindle checkpoint.

A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy.

Fabrication of localized surface plasmon resonance fiber probes using ionic self-assembled gold nanoparticles.

Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high-content screening.