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Chapter 14

Biostatistics

健康科学中的生物统计学概述
健康科学中的生物统计学概述
Biostatistics involves applying statistical concepts to health-related fields such as public health and epidemiology, often with human subjects. This ...
流行病学导论
流行病学导论
Epidemiology studies the patterns, distributions, and factors determining diseases and health conditions in a target population. Its methodology varies ...
患病率和发病率
患病率和发病率
In epidemiology, prevalence refers to the probability of people being affected by a disease in a target population. Conversely, incidence is the ...
敏感性、特异性和预测值
敏感性、特异性和预测值
In health sciences, sensitivity refers to the probability that a diagnostic test shows a positive result when the disease is present. On the other hand, ...
受试者工作特征图
受试者工作特征图
When assessing a diagnostic tool or test for a particular illness, it's crucial to weigh the significance of both sensitivity and specificity. A ...
流行病学研究设计
流行病学研究设计
Consider an example of testing calcium's effect on a woman's bone weight. In an ideal study design, the same woman would be observed in two ...
响应面方法
响应面方法
Response Surface Methodology, or RSM, is a statistical technique that analyzes several input variables or factors potentially influencing a response ...
相对风险
相对风险
Relative risk, or risk ratio, is the ratio of the probability of a disease occurring in the exposed group to the probability in the unexposed or control ...
比值比
比值比
The odds ratio, or cross-product ratio, is the ratio of the odds that a disease occurs upon exposure to a risk factor to the odds that the same disease ...
流行病学中的因果关系
流行病学中的因果关系
Causality, or causation, is fundamentally different from a correlation. Consider a hypothetical correlation between the number of hospitals in a region ...
流行病学研究中的混杂
流行病学研究中的混杂
Confounding refers to the distortion of the estimated association between an exposure and an outcome due to the influence of a third variable, known as a ...
评估和解决混杂因素的策略
评估和解决混杂因素的策略
Confounding affects conclusions about the associations between exposures and outcomes. But, it can be addressed during both the design and analysis ...
因果关系标准:Bradford Hill 标准 - I
因果关系标准:Bradford Hill 标准 - I
Sir Austin Bradford Hill suggested nine criteria for causality, out of which strength, consistency, specificity, and temporality are explained here. The ...
因果关系标准:Bradford Hill 标准 - II
因果关系标准:Bradford Hill 标准 - II
The Bradford Hill criteria for causality include biological gradient, plausibility, coherence, experiment, and analogy. The biological gradient, or ...
流行病学研究中的偏倚
流行病学研究中的偏倚
A bias is a systematic tendency of a quantity's estimate or expected value to be skewed or far from the true value. For example, a thermometer ...
分析流行病学数据的统计方法
分析流行病学数据的统计方法
Various statistical techniques are used to analyze epidemiological data and guide appropriate public health interventions. Consider a study on the ...
爆发调查的步骤
爆发调查的步骤
An outbreak occurs when disease cases unexpectedly exceed normal levels in a specific area and timeframe, such as when multiple people contract a similar ...
疾病监测原则
疾病监测原则
Disease surveillance involves systematic data collection and analysis, which is essential for public health management and disease prevention. ...
纵向研究
纵向研究
Longitudinal studies are research designs involving repeated observation of the same subjects, capturing changes and developments over time. These studies ...
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