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Chapter 14

Biostatistics

健康科学における生物統計学の概要
健康科学における生物統計学の概要
Biostatistics involves applying statistical concepts to health-related fields such as public health and epidemiology, often with human subjects. This ...
疫学入門
疫学入門
Epidemiology studies the patterns, distributions, and factors determining diseases and health conditions in a target population. Its methodology varies ...
有病率と発生率
有病率と発生率
In epidemiology, prevalence refers to the probability of people being affected by a disease in a target population. Conversely, incidence is the ...
感度、特異度、予測値
感度、特異度、予測値
In health sciences, sensitivity refers to the probability that a diagnostic test shows a positive result when the disease is present. On the other hand, ...
受信者の動作特性プロット
受信者の動作特性プロット
When assessing a diagnostic tool or test for a particular illness, it's crucial to weigh the significance of both sensitivity and specificity. A ...
疫学における研究デザイン
疫学における研究デザイン
Consider an example of testing calcium's effect on a woman's bone weight. In an ideal study design, the same woman would be observed in two ...
応答曲面の方法論
応答曲面の方法論
Response Surface Methodology, or RSM, is a statistical technique that analyzes several input variables or factors potentially influencing a response ...
相対リスク
相対リスク
Relative risk, or risk ratio, is the ratio of the probability of a disease occurring in the exposed group to the probability in the unexposed or control ...
オッズ比
オッズ比
The odds ratio, or cross-product ratio, is the ratio of the odds that a disease occurs upon exposure to a risk factor to the odds that the same disease ...
疫学における因果関係
疫学における因果関係
Causality, or causation, is fundamentally different from a correlation. Consider a hypothetical correlation between the number of hospitals in a region ...
疫学研究における交絡
疫学研究における交絡
Confounding refers to the distortion of the estimated association between an exposure and an outcome due to the influence of a third variable, known as a ...
交絡の評価と対処のための戦略
交絡の評価と対処のための戦略
Confounding affects conclusions about the associations between exposures and outcomes. But, it can be addressed during both the design and analysis ...
因果関係の基準:ブラッドフォードヒル基準 - I
因果関係の基準:ブラッドフォードヒル基準 - I
Sir Austin Bradford Hill suggested nine criteria for causality, out of which strength, consistency, specificity, and temporality are explained here. The ...
因果関係の基準:ブラッドフォードヒル基準 - II
因果関係の基準:ブラッドフォードヒル基準 - II
The Bradford Hill criteria for causality include biological gradient, plausibility, coherence, experiment, and analogy. The biological gradient, or ...
疫学研究におけるバイアス
疫学研究におけるバイアス
A bias is a systematic tendency of a quantity's estimate or expected value to be skewed or far from the true value. For example, a thermometer ...
疫学データ解析のための統計的手法
疫学データ解析のための統計的手法
Various statistical techniques are used to analyze epidemiological data and guide appropriate public health interventions. Consider a study on the ...
アウトブレイク調査のステップ
アウトブレイク調査のステップ
An outbreak occurs when disease cases unexpectedly exceed normal levels in a specific area and timeframe, such as when multiple people contract a similar ...
疾病サーベイランスの原則
疾病サーベイランスの原則
Disease surveillance involves systematic data collection and analysis, which is essential for public health management and disease prevention. ...
縦断的研究
縦断的研究
Longitudinal studies are research designs involving repeated observation of the same subjects, capturing changes and developments over time. These studies ...
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