Results: Non-invasive Monitoring for Brain Metastasis Outgrowth
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Conclusion
副本
The overall goal of this microsurgical injection of cancer cells through the carotid artery is to produce consistent in vivo experimental brain metastasis models in mice. So this method can help answer key questions in the brain metastasis field,
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Brain metastasis has become an urgent unmet medical need as its incidence has increased while therapeutic options have remained palliative. Creating experimental animal models of brain metastasis via intracarotid arterial injection of cancer cells facilitates mechanistic studies of the disease biology and evaluation of novel intervention regimens.