Results: Characterization of the Nuclear Deformation
5:29
Conclusion
副本
This method can help answer key questions in the nuclear mechanics field. For example, what is the force required to deform the nucleus in a cell? What are the contributions of cellular and nuclear components to nuclear resistance to deformation?<
登录或开始您的免费试用以访问此内容
In this protocol, we describe a micropipette method to directly apply a controlled force to the nucleus in a living cell. This assay allows interrogation of nuclear mechanical properties in the living, adherent cell.