缺氧敏感的嵌合抗原受体-T 细胞的生成和功能验证

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09:12 min

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June 14th, 2024

DOI :

10.3791/66697-v

June 14th, 2024

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Ying Xue*¹, Yunyu Mao*², Qibin Liao³, Chen Zhao⁴, Xiaoyan Zhang¹^,²^,⁴, Jianqing Xu¹^,²^,⁴

¹Institutes of Biomedical Sciences, Fudan University, ²Clinical Center of Biotherapy at Zhongshan Hospital, Fudan University, ³Department of Oncology and Bio-therapeutic Center, Shenzhen Third People's Hospital, Southern University of Science and Technology, ⁴Shanghai Public Health Clinical Center, Fudan University

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T CAR T

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Introduction

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Development of Hypoxia‐Responsive CAR‐T Cells via Lentiviral Transduction

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Flow Cytometric Assessment of Oxygen‐Dependent CAR Expression in CAR‐T cells

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In Vitro Assessment of Cytotoxicity Mediated by Hypoxia‐Sensitive CAR‐T Cells

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