Generation and Functional Verification of Hypoxia-Sensitive Chimeric Antigen Receptor-T Cells
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09:12 min
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June 14th, 2024
DOI :
June 14th, 2024
•1Institutes of Biomedical Sciences, Fudan University, 2Clinical Center of Biotherapy at Zhongshan Hospital, Fudan University, 3Department of Oncology and Bio-therapeutic Center, Shenzhen Third People's Hospital, Southern University of Science and Technology, 4Shanghai Public Health Clinical Center, Fudan University
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Chapters in this video
0:00
Introduction
1:43
Development of Hypoxia‐Responsive CAR‐T Cells via Lentiviral Transduction
4:32
Flow Cytometric Assessment of Oxygen‐Dependent CAR Expression in CAR‐T cells
7:14
In Vitro Assessment of Cytotoxicity Mediated by Hypoxia‐Sensitive CAR‐T Cells
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