Heikki Rauvala

Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells.

Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease.

N -Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth.

Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice.

Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation.

Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis.

Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory.

Effects of targeted overexpression of pleiotrophin on postnatal bone development.

Activity blockade increases the number of functional synapses in the hippocampus of newborn rats.

AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats.

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

[The dynamic synapse].

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins.

Increased expression of beta6-integrin in skin leads to spontaneous development of chronic wounds.

HB-GAM/Pleiotrophin and Midkine are differently expressed and distributed during retinoic acid-induced neural differentiation of P19 cells.

The role of ECM molecules in activity-dependent synaptic development and plasticity.

HB-GAM inhibits proliferation and enhances differentiation of neural stem cells.

Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCgamma pathway, reduced anxiety, and facilitated learning.

Regulation of monocyte migration by amphoterin (HMGB1).

Impaired behavioural flexibility and memory in mice lacking GDNF family receptor alpha2.

Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration.

Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock.

Behavioural phenotypes of hypomorphic KCC2-deficient mice.

The two thrombospondin type I repeat domains of the heparin-binding growth-associated molecule bind to heparin/heparan sulfate and regulate neurite extension and plasticity in hippocampal neurons.

The two thrombospondin type I repeat domains of HB-GAM display a cooperative function in N-syndecan binding and regulation of synaptic plasticity.

Solution structures of the first and fourth TSR domains of F-spondin.

The layered fold of the TSR domain of P. falciparum TRAP contains a heparin binding site.

N-syndecan deficiency impairs neural migration in brain.

Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin).

Interview with Dr. Heikki Rauvala regarding pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin). Interview by Marco E Bianchi.

Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage.

Shedded neuronal ICAM-5 suppresses T-cell activation.

High mobility group box 1 protein induction by Mycobacterium bovis BCG.

RAGE as a receptor of HMGB1 (Amphoterin): roles in health and disease.

Sensory neurons from N-syndecan-deficient mice are defective in survival.

High mobility group box 1 protein as a marker of hepatocellular injury in human liver transplantation.

Neuronal regulation of immune responses in the central nervous system.

Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons.

Circulating levels of a soluble form of receptor for advanced glycation end products and high-mobility group box chromosomal protein 1 in patients with acute pancreatitis.

Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors.

Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice.

Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin.

High mobility group box-1 (HMGB1; amphoterin) is required for zebrafish brain development.

HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator.

Evaluation of social and physical enrichment in modulation of behavioural phenotype in C57BL/6J female mice.

Crystal structure and role of glycans and dimerization in folding of neuronal leucine-rich repeat protein AMIGO-1.

AMIGO is an auxiliary subunit of the Kv2.1 potassium channel.

Expression of GluK1c underlies the developmental switch in presynaptic kainate receptor function.

RAGE-mediated cell signaling.

CD73 is a major regulator of adenosinergic signalling in mouse brain.

HMGB1 contributes to regeneration after spinal cord injury in adult zebrafish.