Department of Developmental Biology
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Genes directly controlled by CtrA, a master regulator of the Caulobacter cell cycle.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2002 | Pubmed ID: 11930012
Dynamic localization of proteins and DNA during a bacterial cell cycle.
Nature reviews. Molecular cell biology Mar, 2002 | Pubmed ID: 11994737
Control of chromosome replication in caulobacter crescentus.
Annual review of microbiology , 2002 | Pubmed ID: 12142494
A dynamically localized histidine kinase controls the asymmetric distribution of polar pili proteins.
The EMBO journal Sep, 2002 | Pubmed ID: 12198144
DNA methylation affects the cell cycle transcription of the CtrA global regulator in Caulobacter.
The EMBO journal Sep, 2002 | Pubmed ID: 12234936
A signal transduction protein cues proteolytic events critical to Caulobacter cell cycle progression.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12237413
Identification of a localization factor for the polar positioning of bacterial structural and regulatory proteins.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12370432
The CtrA response regulator essential for Caulobacter crescentus cell-cycle progression requires a bipartite degradation signal for temporally controlled proteolysis.
Journal of molecular biology Nov, 2002 | Pubmed ID: 12445780
Generating and exploiting polarity in bacteria.
Science (New York, N.Y.) Dec, 2002 | Pubmed ID: 12471245
TmRNA is required for correct timing of DNA replication in Caulobacter crescentus.
Journal of bacteriology Jan, 2003 | Pubmed ID: 12511504
Functions of the CckA histidine kinase in Caulobacter cell cycle control.
Molecular microbiology Mar, 2003 | Pubmed ID: 12603734
tmRNA in Caulobacter crescentus is cell cycle regulated by temporally controlled transcription and RNA degradation.
Journal of bacteriology Mar, 2003 | Pubmed ID: 12618446
Temporal and spatial regulation in prokaryotic cell cycle progression and development.
Annual review of biochemistry , 2003 | Pubmed ID: 12651741
Cell-cycle-regulated expression and subcellular localization of the Caulobacter crescentus SMC chromosome structural protein.
Journal of bacteriology May, 2003 | Pubmed ID: 12730166
Polar localization of replicon origins in the multipartite genomes of Agrobacterium tumefaciens and Sinorhizobium meliloti.
Journal of bacteriology Jun, 2003 | Pubmed ID: 12754237
Bacterial cell division spirals into control.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2003 | Pubmed ID: 12810947
Fluorescence bleaching reveals asymmetric compartment formation prior to cell division in Caulobacter.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2003 | Pubmed ID: 12824468
A lytic transglycosylase homologue, PleA, is required for the assembly of pili and the flagellum at the Caulobacter crescentus cell pole.
Molecular microbiology Jul, 2003 | Pubmed ID: 12828633
Identification of long intergenic repeat sequences associated with DNA methylation sites in Caulobacter crescentus and other alpha-proteobacteria.
Journal of bacteriology Aug, 2003 | Pubmed ID: 12897020
A bacterial cell-cycle regulatory network operating in time and space.
Science (New York, N.Y.) Sep, 2003 | Pubmed ID: 14512618
Codon usage between genomes is constrained by genome-wide mutational processes.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2004 | Pubmed ID: 14990797
Oscillating global regulators control the genetic circuit driving a bacterial cell cycle.
Science (New York, N.Y.) May, 2004 | Pubmed ID: 15087506
Recruitment of a cytoplasmic response regulator to the cell pole is linked to its cell cycle-regulated proteolysis.
Proceedings of the National Academy of Sciences of the United States of America May, 2004 | Pubmed ID: 15123835
An actin-like gene can determine cell polarity in bacteria.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15159537
Rapid and sequential movement of individual chromosomal loci to specific subcellular locations during bacterial DNA replication.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15178755
The topoisomerase IV ParC subunit colocalizes with the Caulobacter replisome and is required for polar localization of replication origins.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15178756
A genetic oscillator and the regulation of cell cycle progression in Caulobacter crescentus.
Cell cycle (Georgetown, Tex.) Oct, 2004 | Pubmed ID: 15467452
Spatial complexity of mechanisms controlling a bacterial cell cycle.
Current opinion in microbiology Dec, 2004 | Pubmed ID: 15556028
A membrane metalloprotease participates in the sequential degradation of a Caulobacter polarity determinant.
Molecular microbiology Feb, 2005 | Pubmed ID: 15686556
MreB actin-mediated segregation of a specific region of a bacterial chromosome.
Cell Feb, 2005 | Pubmed ID: 15707892
An open letter to Elias Zerhouni.
Science (New York, N.Y.) Mar, 2005 | Pubmed ID: 15746409
The structure and function of the bacterial chromosome.
Current opinion in genetics & development Apr, 2005 | Pubmed ID: 15797198
The choreographed dynamics of bacterial chromosomes.
Trends in microbiology May, 2005 | Pubmed ID: 15866039
Conserved modular design of an oxygen sensory/signaling network with species-specific output.
Proceedings of the National Academy of Sciences of the United States of America May, 2005 | Pubmed ID: 15911751
The bacterial nucleoid: a highly organized and dynamic structure.
Journal of cellular biochemistry Oct, 2005 | Pubmed ID: 15988757
Identification of borinic esters as inhibitors of bacterial cell growth and bacterial methyltransferases, CcrM and MenH.
Journal of medicinal chemistry Nov, 2005 | Pubmed ID: 16279806
DnaA coordinates replication initiation and cell cycle transcription in Caulobacter crescentus.
Molecular microbiology Dec, 2005 | Pubmed ID: 16313620
Two independent spiral structures control cell shape in Caulobacter.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2005 | Pubmed ID: 16344481
Cytokinesis signals truncation of the PodJ polarity factor by a cell cycle-regulated protease.
The EMBO journal Jan, 2006 | Pubmed ID: 16395329
DnaA couples DNA replication and the expression of two cell cycle master regulators.
The EMBO journal Jan, 2006 | Pubmed ID: 16395331
The bifunctional FtsK protein mediates chromosome partitioning and cell division in Caulobacter.
Journal of bacteriology Feb, 2006 | Pubmed ID: 16452433
A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator.
Cell Feb, 2006 | Pubmed ID: 16469700
A phospho-signaling pathway controls the localization and activity of a protease complex critical for bacterial cell cycle progression.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2006 | Pubmed ID: 16829582
Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentus.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2006 | Pubmed ID: 16829583
MipZ, a spatial regulator coordinating chromosome segregation with cell division in Caulobacter.
Cell Jul, 2006 | Pubmed ID: 16839883
Chromosome organization and segregation in bacteria.
Journal of structural biology Nov, 2006 | Pubmed ID: 16860572
High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons.
Nature biotechnology May, 2007 | Pubmed ID: 17401361
The push and pull of the bacterial cytoskeleton.
Trends in cell biology May, 2007 | Pubmed ID: 17434308
An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site.
Science (New York, N.Y.) Jun, 2007 | Pubmed ID: 17588934
Spatial complexity and control of a bacterial cell cycle.
Current opinion in biotechnology Aug, 2007 | Pubmed ID: 17709236
Caulobacter crescentus as a whole-cell uranium biosensor.
Applied and environmental microbiology Dec, 2007 | Pubmed ID: 17905881
Cell cycle regulation in Caulobacter: location, location, location.
Journal of cell science Oct, 2007 | Pubmed ID: 17928306
A DNA methylation ratchet governs progression through a bacterial cell cycle.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17942674
A comprehensive set of plasmids for vanillate- and xylose-inducible gene expression in Caulobacter crescentus.
Nucleic acids research , 2007 | Pubmed ID: 17959646
Getting organized--how bacterial cells move proteins and DNA.
Nature reviews. Microbiology Jan, 2008 | Pubmed ID: 18059290
Systems biology of Caulobacter.
Annual review of genetics , 2007 | Pubmed ID: 18076330
Small non-coding RNAs in Caulobacter crescentus.
Molecular microbiology May, 2008 | Pubmed ID: 18373523
Architecture and inherent robustness of a bacterial cell-cycle control system.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2008 | Pubmed ID: 18685108
SpoT regulates DnaA stability and initiation of DNA replication in carbon-starved Caulobacter crescentus.
Journal of bacteriology Oct, 2008 | Pubmed ID: 18723629
Super-resolution imaging in live Caulobacter crescentus cells using photoswitchable EYFP.
Nature methods Nov, 2008 | Pubmed ID: 18794860
A polymeric protein anchors the chromosomal origin/ParB complex at a bacterial cell pole.
Cell Sep, 2008 | Pubmed ID: 18805088
Caulobacter requires a dedicated mechanism to initiate chromosome segregation.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2008 | Pubmed ID: 18824683
A bacterial control circuit integrates polar localization and proteolysis of key regulatory proteins with a phospho-signaling cascade.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2008 | Pubmed ID: 18946044
Feedback control of DnaA-mediated replication initiation by replisome-associated HdaA protein in Caulobacter.
Journal of bacteriology Sep, 2009 | Pubmed ID: 19633089
System-level design of bacterial cell cycle control.
FEBS letters Dec, 2009 | Pubmed ID: 19766635
Caulobacter PopZ forms a polar subdomain dictating sequential changes in pole composition and function.
Molecular microbiology Apr, 2010 | Pubmed ID: 20149103
High-throughput identification of protein localization dependency networks.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20176934
Bacterial chromosome organization and segregation.
Cold Spring Harbor perspectives in biology Feb, 2010 | Pubmed ID: 20182613
Cell pole-specific activation of a critical bacterial cell cycle kinase.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2010 | Pubmed ID: 20351295
DipM links peptidoglycan remodelling to outer membrane organization in Caulobacter.
Molecular microbiology Jul, 2010 | Pubmed ID: 20497504
Polar remodeling and histidine kinase activation, which is essential for Caulobacter cell cycle progression, are dependent on DNA replication initiation.
Journal of bacteriology Aug, 2010 | Pubmed ID: 20525830
CrfA, a small noncoding RNA regulator of adaptation to carbon starvation in Caulobacter crescentus.
Journal of bacteriology Sep, 2010 | Pubmed ID: 20601471
A spindle-like apparatus guides bacterial chromosome segregation.
Nature cell biology Aug, 2010 | Pubmed ID: 20657594
The caulobacter Tol-Pal complex is essential for outer membrane integrity and the positioning of a polar localization factor.
Journal of bacteriology Oct, 2010 | Pubmed ID: 20693330
Imaging-based identification of a critical regulator of FtsZ protofilament curvature in Caulobacter.
Molecular cell Sep, 2010 | Pubmed ID: 20864042
Superresolution imaging of targeted proteins in fixed and living cells using photoactivatable organic fluorophores.
Journal of the American Chemical Society Nov, 2010 | Pubmed ID: 20936809
Initiating bacterial mitosis: understanding the mechanism of ParA-mediated chromosome segregation.
Cell cycle (Georgetown, Tex.) Oct, 2010 | Pubmed ID: 20948303
An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2010 | Pubmed ID: 20956288
Bacterial polarity.
Current opinion in cell biology Feb, 2011 | Pubmed ID: 21095111
The architecture and conservation pattern of whole-cell control circuitry.
Journal of molecular biology May, 2011 | Pubmed ID: 21371478
Super-resolution imaging of the nucleoid-associated protein HU in Caulobacter crescentus.
Biophysical journal Apr, 2011 | Pubmed ID: 21463569
Regulatory response to carbon starvation in Caulobacter crescentus.
PloS one , 2011 | Pubmed ID: 21494595
Assembly of the Caulobacter cell division machine.
Molecular microbiology Jun, 2011 | Pubmed ID: 21542856
Mutations in the nucleotide binding pocket of MreB can alter cell curvature and polar morphology in Caulobacter.
Molecular microbiology Jul, 2011 | Pubmed ID: 21564339
Fifty years after Jacob and Monod: what are the unanswered questions in molecular biology?
Molecular cell May, 2011 | Pubmed ID: 21748867
The essential genome of a bacterium.
Molecular systems biology , 2011 | Pubmed ID: 21878915
Exploring protein superstructures and dynamics in live bacterial cells using single-molecule and superresolution imaging.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21909887
An SMC ATPase mutant disrupts chromosome segregation in Caulobacter.
Molecular microbiology Dec, 2011 | Pubmed ID: 21923769
The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation.
Molecular cell Oct, 2011 | Pubmed ID: 22017872
Three-dimensional superresolution colocalization of intracellular protein superstructures and the cell surface in live Caulobacter crescentus.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22031697
Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization.
Molecular microbiology Feb, 2012 | Pubmed ID: 22211578
Three-dimensional super-resolution imaging of the midplane protein FtsZ in live Caulobacter crescentus cells using astigmatism.
Chemphyschem : a European journal of chemical physics and physical chemistry Mar, 2012 | Pubmed ID: 22262316
Osmolality-dependent relocation of penicillin-binding protein PBP2 to the division site in Caulobacter crescentus.
Journal of bacteriology Jun, 2012 | Pubmed ID: 22505677
Life in a three-dimensional grid.
The Journal of biological chemistry Nov, 2012 | Pubmed ID: 23007401
Chromosome architecture is a key element of bacterial cellular organization.
Cellular microbiology Jan, 2013 | Pubmed ID: 23078580
Caulobacter chromosome in vivo configuration matches model predictions for a supercoiled polymer in a cell-like confinement.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2013 | Pubmed ID: 23319648
Quantitative multicolor subdiffraction imaging of bacterial protein ultrastructures in three dimensions.
Nano letters Mar, 2013 | Pubmed ID: 23414562
Retrospective. Francois Jacob (1920-2013).
Science (New York, N.Y.) May, 2013 | Pubmed ID: 23704565
Branched signal wiring of an essential bacterial cell-cycle phosphotransfer protein.
Structure (London, England : 1993) Sep, 2013 | Pubmed ID: 23932593
Oligomerization and higher-order assembly contribute to sub-cellular localization of a bacterial scaffold.
Molecular microbiology Nov, 2013 | Pubmed ID: 24102805
Global methylation state at base-pair resolution of the Caulobacter genome throughout the cell cycle.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2013 | Pubmed ID: 24218615
The functions of DNA methylation by CcrM in Caulobacter crescentus: a global approach.
Nucleic acids research Apr, 2014 | Pubmed ID: 24398711
Bacterial scaffold directs pole-specific centromere segregation.
Proceedings of the National Academy of Sciences of the United States of America May, 2014 | Pubmed ID: 24778223
ClpXP and ClpAP proteolytic activity on divisome substrates is differentially regulated following the Caulobacter asymmetric cell division.
Molecular microbiology Sep, 2014 | Pubmed ID: 24989075
The coding and noncoding architecture of the Caulobacter crescentus genome.
PLoS genetics Jul, 2014 | Pubmed ID: 25078267
Replication initiator DnaA binds at the Caulobacter centromere and enables chromosome segregation.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25349407
Cell fate regulation governed by a repurposed bacterial histidine kinase.
PLoS biology Oct, 2014 | Pubmed ID: 25349992
The global regulatory architecture of transcription during the Caulobacter cell cycle.
PLoS genetics Jan, 2015 | Pubmed ID: 25569173
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