Shaun R. Brinsmade

The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state.

The eutD gene of Salmonella enterica encodes a protein with phosphotransacetylase enzyme activity.

Minimal functions and physiological conditions required for growth of salmonella enterica on ethanolamine in the absence of the metabolosome.

Mutation of phosphotransacetylase but not isocitrate lyase reduces the virulence of Salmonella enterica serovar Typhimurium in mice.

In vivo and in vitro analyses of single-amino acid variants of the Salmonella enterica phosphotransacetylase enzyme provide insights into the function of its N-terminal domain.

Regulation of CodY activity through modulation of intracellular branched-chain amino acid pools.

Involvement of protein acetylation in glucose-induced transcription of a stress-responsive promoter.

Dissecting complex metabolic integration provides direct genetic evidence for CodY activation by guanine nucleotides.

GTP dysregulation in Bacillus subtilis cells lacking (p)ppGpp results in phenotypic amino acid auxotrophy and failure to adapt to nutrient downshift and regulate biosynthesis genes.

Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY.

Genome Sequence of the Clinical Isolate Staphylococcus aureus subsp. aureus Strain UAMS-1.

Intermediate Levels of Bacillus subtilis CodY Activity Are Required for Derepression of the Branched-Chain Amino Acid Permease, BraB.

A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus.

CodY, a master integrator of metabolism and virulence in Gram-positive bacteria.

Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureus.

Guanine limitation results in CodY-dependent and -independent alteration of physiology and gene expression.