Jeffrey D. Cirillo

Entry into host cells by Legionella.

Genetic and phenotypic differences between Legionella pneumophila strains.

Role of the Legionella pneumophila rtxA gene in amoebae.

Bifunctional constructs of aspirin and ibuprofen (non-steroidal anti-inflammatory drugs; NSAIDs) that express antibacterial and alkylation activities.

Identification of a gene that affects the efficiency of host cell infection by Legionella pneumophila in a temperature-dependent fashion.

Infection of murine macrophage cell lines by Legionella pneumophila.

Evidence that hsp90 is involved in the altered interactions of Acanthamoeba castellanii variants with bacteria.

Identification of two Mycobacterium marinum loci that affect interactions with macrophages.

Identification of Mycobacterium avium genes that affect invasion of the intestinal epithelium.

Molecular properties and antibacterial activity of the methyl and ethyl ester derivatives of ampicillin.

Identification of Mycobacterium marinum macrophage infection mutants.

A Mycobacterium marinum mel2 mutant is defective for growth in macrophages that produce reactive oxygen and reactive nitrogen species.

The Mycobacterium marinum mel2 locus displays similarity to bacterial bioluminescence systems and plays a role in defense against reactive oxygen and nitrogen species.

Derivatives of cephalothin that inhibit ampicillin resistant Escherichia coli.

Antibacterial activity of dipeptide constructs of acetylsalicylic acid and nicotinic acid.

Identification of Mycobacterium avium pathogenicity island important for macrophage and amoeba infection.

Virulent mycobacteria and the many aspects of macrophage uptake.

Use of gene dosage effects for a whole-genome screen to identify Mycobacterium marinum macrophage infection loci.

Non-opsonic phagocytosis of Legionella pneumophila by macrophages is mediated by phosphatidylinositol 3-kinase.

Protection of Mycobacterium tuberculosis from reactive oxygen species conferred by the mel2 locus impacts persistence and dissemination.

Mycobacterium tuberculosis interferes with the response to infection by inducing the host EphA2 receptor.

Efficacy of using sutures treated with povidone-iodine or chlorhexidine for preventing growth of Staphylococcus and Escherichia coli.

Application of optical imaging to study of extrapulmonary spread by tuberculosis.

Four hydrazide compounds that inhibit the growth of mycobacterium tuberculosis.

Design of ciprofloxacin derivatives that inhibit growth of methicillin resistant Staphylococcus aureus (MRSA) and methicillin susceptible Staphylococcus aureus (MSSA).

Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice.

Reporter enzyme fluorescence (REF) imaging and quantification of tuberculosis in live animals.

Pseudomonas aeruginosa PAO1 virulence factors and poplar tree response in the rhizosphere.

Indole and 7-hydroxyindole diminish Pseudomonas aeruginosa virulence.

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos.

Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis.

Whole-body imaging of infection using fluorescence.

Whole-body imaging of infection using bioluminescence.

Fiber optic microendoscopy for preclinical study of bacterial infection dynamics.

Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity.

Random inducible controlled expression (RICE) for identification of mycobacterial virulence genes.

Antibacterial activities of gold and silver nanoparticles against Escherichia coli and bacillus Calmette-Guérin.

Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe.

The EAL domain containing protein STM2215 (rtn) is needed during Salmonella infection and has cyclic di-GMP phosphodiesterase activity.

Molecular analysis of the Mycobacterium tuberculosis lux-like mel2 operon.

Real-time bioluminescence imaging of mixed mycobacterial infections.

Bacteria repelling on highly-ordered alumina-nanopore structures.

Antibacterial Derivatives of Ciprofloxacin to Inhibit Growth of Necrotizing Fasciitis Associated Penicillin Resistant Escherichia coli.

The Caenorhabditis elegans p38 MAPK Gene plays a key role in protection from mycobacteria.

Application of Fluorescent Protein Expressing Strains to Evaluation of Anti-Tuberculosis Therapeutic Efficacy In Vitro and In Vivo.

Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4+ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation.

Real-time Imaging of Mycobacterium tuberculosis, Using a Novel Near-Infrared Fluorescent Substrate.

New directions using reporter enzyme fluorescence (REF) as a tuberculosis diagnostic platform.

Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein.

Thioaptamer targeted discoidal microparticles increase self immunity and reduce Mycobacterium tuberculosis burden in mice.

Guinea pig infection with the intracellular pathogen Rhodococcus equi.