Chao Lu

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.

OPLS3e: Extending Force Field Coverage for Drug-Like Small Molecules.

H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.

Genome analyses of the new model protist Euplotes vannus focusing on genome rearrangement and resistance to environmental stressors.

Ultra-Thin Conductive Graphitic Carbon Nitride Assembly through van der Waals Epitaxy toward High-Energy-Density Flexible Supercapacitors.

In situ synthesized PEO/NBR composite ionogels for high-performance all-solid-state supercapacitors.

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.

Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells.

Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells.

Flexible and Electroactive Ionogel Graphene Composite Actuator.

All-Temperature Flexible Supercapacitors Enabled by Antifreezing and Thermally Stable Hydrogel Electrolyte.

and Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice.

Single-Atom Catalytic Materials for Advanced Battery Systems.

Single-atom Catalytic Materials for Lean-electrolyte Ultrastable Lithium-Sulfur Batteries.

Latest Advances in Flexible Symmetric Supercapacitors: From Material Engineering to Wearable Applications.

Chromosome 3p loss of heterozygosity and reduced expression of H3K36me3 correlate with longer relapse-free survival in sacral conventional chordoma.

Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.

The INO80 Complex Regulates Epigenetic Inheritance of Heterochromatin.

Decoding the function of an oncogenic transcription factor: finding the first responders.

Functional interrogation of DNA damage response variants with base editing screens.

Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.

Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma.

The interplay between DNA and histone methylation: molecular mechanisms and disease implications.

Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.

The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin.

OPLS4: Improving Force Field Accuracy on Challenging Regimes of Chemical Space.

Highly Sensitive Ultrastable Electrochemical Sensor Enabled by Proton-Coupled Electron Transfer.

Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors.

Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.

Pparg signaling controls bladder cancer subtype and immune exclusion.

Nanostructure Engineering of Graphitic Carbon Nitride for Electrochemical Applications.

Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks.

CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.

The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly.

H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells.

Porous g-CN covered MOF-derived nanocarbon materials for high-performance supercapacitors.

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis.

Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas.

Reliable and Accurate Prediction of Single-Residue p Values through Free Energy Perturbation Calculations.