Department of Neurobiology and Anatomy,
Program in Cancer Cell Biology,
Department of Neurobiology and Anatomy, Program in Cancer Cell Biology
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Dynamin2 and cortactin regulate actin assembly and filament organization.
Current biology : CB Oct, 2002 | Pubmed ID: 12419186
Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion.
Current biology : CB Mar, 2003 | Pubmed ID: 12620186
MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.
The EMBO journal Jul, 2003 | Pubmed ID: 12839996
Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton.
Molecular biology of the cell Aug, 2003 | Pubmed ID: 12925758
Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages.
Journal of cell science Jan, 2004 | Pubmed ID: 14676277
Characterization of an ankyrin repeat-containing Shank2 isoform (Shank2E) in liver epithelial cells.
The Biochemical journal May, 2004 | Pubmed ID: 14977424
Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization.
The Journal of cell biology Mar, 2004 | Pubmed ID: 15024035
Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.
The Biochemical journal Jun, 2004 | Pubmed ID: 15030313
Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells.
The Journal of cell biology Jul, 2004 | Pubmed ID: 15263018
Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110.
Molecular and cellular biology Sep, 2004 | Pubmed ID: 15314167
Cortactin overexpression regulates actin-related protein 2/3 complex activity, motility, and invasion in carcinomas with chromosome 11q13 amplification.
Cancer research Aug, 2006 | Pubmed ID: 16912177
Overexpression of cyclin D1 and cortactin is primarily independent of gene amplification in salivary gland adenoid cystic carcinoma.
Oral oncology Sep, 2007 | Pubmed ID: 17113340
PI3K activation is required for PMA-directed activation of cSrc by AFAP-110.
American journal of physiology. Cell physiology Jul, 2007 | Pubmed ID: 17360811
Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer.
Clinical & experimental metastasis , 2008 | Pubmed ID: 18324357
Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells.
Journal of cell science Jul, 2008 | Pubmed ID: 18577577
Cortactin branches out: roles in regulating protrusive actin dynamics.
Cell motility and the cytoskeleton Sep, 2008 | Pubmed ID: 18615630
Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers.
The Journal of biological chemistry Jul, 2009 | Pubmed ID: 19457864
Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function.
Journal of cancer science & therapy Nov, 2009 | Pubmed ID: 20505783
Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.
Journal of cell science Nov, 2010 | Pubmed ID: 20980387
Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence.
PloS one , 2010 | Pubmed ID: 21079800
Revisiting the ERK/Src cortactin switch.
Communicative & integrative biology Mar, 2011 | Pubmed ID: 21655441
Further insights into cortactin conformational regulation.
Bioarchitecture 1, 2011 | Pubmed ID: 21866257
Effects of Tobacco Smoking and Nicotine on Cancer Treatment.
Pharmacotherapy Aug, 2012 | Pubmed ID: 22887142
Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation.
PloS one , 2012 | Pubmed ID: 22952966
Effects of tobacco smoking and nicotine on cancer treatment.
Pharmacotherapy Oct, 2012 | Pubmed ID: 23033231
Src binds cortactin through an SH2 domain cystine-mediated linkage.
Journal of cell science Dec, 2012 | Pubmed ID: 23097045
Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.
Nucleic acids research May, 2013 | Pubmed ID: 23519612
Metastatic MTLn3 and non-metastatic MTC adenocarcinoma cells can be differentiated by Pseudomonas aeruginosa.
Biology open , 2013 | Pubmed ID: 24143275
NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis.
Molecular cancer research : MCR Jan, 2014 | Pubmed ID: 24202705
Recently identified biomarkers that promote lymph node metastasis in head and neck squamous cell carcinoma.
Cancers , 2011 | Pubmed ID: 24212639
NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner.
Molecular cancer research : MCR May, 2014 | Pubmed ID: 24574519
Use of high frequency ultrasound to monitor cervical lymph node alterations in mice.
PloS one , 2014 | Pubmed ID: 24955984
Tumor and stromal-based contributions to head and neck squamous cell carcinoma invasion.
Cancers , 2015 | Pubmed ID: 25734659
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