whole-brain-single-cell-imaging-analysis-intact-neonatal-mouse-brains

Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy

Tissue clearing followed by light-sheet microscopy (LSFM) enables cellular-resolution imaging of intact brain structure, allowing quantitative analysis of ...

isolation-of-preadipocytes-from-broiler-chick-embryos

Isolation of Preadipocytes from Broiler Chick Embryos

Primary preadipocytes are a valuable experimental system for understanding the molecular pathways that control adipocyte differentiation and metabolism. ...

University of Tennessee

The University of North Carolina at Greensboro

The purpose of this paper is to serve as a template for greater understanding for the practicing radiologist about key steps to perform multimodality computer analysis of MRI images, specifically in multiple sclerosis patients. With this understanding, radiologists will be better equipped about how best to process and analyze MRI imaging data and obtain accurate quantitative information for MS patient evaluation. A secondary intent of this article is to improve radiologist understanding of how artificial intelligence will be employed in the future for better patient stratification, and for evaluation of response to therapy in both clinical care and drug trials.

Multimodal Image Analysis for Assessing Multiple Sclerosis and Future Prospects Powered by Artificial Intelligence.

Modern broiler chickens are incredibly efficient, but they accumulate more adipose tissue than is physiologically necessary due to inadvertent consequences of selection for rapid growth. Accumulation of excess adipose tissue wastes feed in birds raised for market, and it compromises well-being in broiler-breeders. Studies driven by the obesity epidemic in humans demonstrate that the fatty acid profile of the diet influences adipose tissue growth and metabolism in ways that can be manipulated to reduce fat accretion. Omega-3 polyunsaturated fatty acids (n-3 PUFA) can inhibit adipocyte differentiation, induce fatty acid oxidation, and enhance energy expenditure, all of which can counteract the accretion of excess adipose tissue. This mini-review summarizes efforts to counteract the tendency for fat accretion in broilers by enriching the diet in n-3 PUFA.

Minjeong Kim

Department of Animal Science

University of Tennessee

Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy

Isolation of Preadipocytes from Broiler Chick Embryos