Marcelo D. Carattino

Syntaxin 1A regulates ENaC via domain-specific interactions.

Arachidonic acid regulates surface expression of epithelial sodium channels.

Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits.

Epithelial Na+ channels are activated by laminar shear stress.

Epithelial sodium channels are activated by furin-dependent proteolysis.

Mutations in the pore region modify epithelial sodium channel gating by shear stress.

Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.

Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

Lack of a role of membrane-protein interactions in flow-dependent activation of ENaC.

Role of proteolysis in the activation of epithelial sodium channels.

Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel.

Effect of aldosterone on BK channel expression in mammalian cortical collecting duct.

Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation.

Novel determinants of epithelial sodium channel gating within extracellular thumb domains.

ENaC at the cutting edge: regulation of epithelial sodium channels by proteases.

Conformational changes associated with proton-dependent gating of ASIC1a.

Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel.

Clues to renal sodium retention.

Second transmembrane domain modulates epithelial sodium channel gating in response to shear stress.

Base of the thumb domain modulates epithelial sodium channel gating.

Insights into the mechanism of pore opening of acid-sensing ion channel 1a.

Structural mechanisms underlying the function of epithelial sodium channel/acid-sensing ion channel.

TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage site.

Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity.

Inhibitory tract traps the epithelial Na+ channel in a low activity conformation.

Cation transport goes with the flow.

Role of the wrist domain in the response of the epithelial sodium channel to external stimuli.

Gating transitions in the palm domain of ASIC1a.

ENaC regulation by proteases and shear stress.

Bladder filling and voiding affect umbrella cell tight junction organization and function.

Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase.

Independent contribution of extracellular proton binding sites to ASIC1a activation.

Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia.

Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease.

Intracellular Na+ regulates epithelial Na+ channel maturation.

Increased urothelial paracellular transport promotes cystitis.

Cell-specific regulation of L-WNK1 by dietary K.

The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization.

Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel.

Urothelial Tight Junction Barrier Dysfunction Sensitizes Bladder Afferents.

Expression and Analysis of Flow-regulated Ion Channels in Oocytes.

Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells.

ASIC3 fine-tunes bladder sensory signaling.

Molecular basis of inhibition of acid sensing ion channel 1A by diminazene.

Urinary K promotes irritative voiding symptoms and pain in the face of urothelial barrier dysfunction.

Renal sensory nerves increase sympathetic nerve activity and blood pressure in 2-kidney 1-clip hypertensive mice.

Murine epithelial sodium (Na) channel regulation by biliary factors.

Expression and distribution of PIEZO1 in the mouse urinary tract.

Molecular determinants of afferent sensitization in a rat model of cystitis with urothelial barrier dysfunction.

Acid-sensing ion channels in sensory signaling.

Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.

The Urothelium: Life in a Liquid Environment.

Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception.

Acid-sensing ion channels modulate bladder nociception.

Bladder infection with uropathogenic increases the excitability of afferent neurons.

Studies of ultrastructure, gene expression, and marker analysis reveal that mouse bladder PDGFRA interstitial cells are fibroblasts.

Functional characterization of ion channels expressed in kidney organoids derived from human induced pluripotent stem cells.