Adam C. Resnick

Inositol polyphosphate multikinase: metabolic architect of nuclear inositides.

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis.

Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene.

Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.

The genetic landscape of the childhood cancer medulloblastoma.

Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB.

Spinal cord ependymomas and myxopapillary ependymomas in the first 2 decades of life: a clinicopathological and immunohistochemical characterization of 19 cases.

Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas.

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.

Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas.

A Novel Inositol Pyrophosphate Phosphatase in Saccharomyces cerevisiae: Siw14 PROTEIN SELECTIVELY CLEAVES THE β-PHOSPHATE FROM 5-DIPHOSPHOINOSITOL PENTAKISPHOSPHATE (5PP-IP5).

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.

BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas.

The biorepository portal toolkit: an honest brokered, modular service oriented software tool set for biospecimen-driven translational research.

Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms.

MYB-QKI drives childhood brain tumors via tripartite mechanism.

Shared ACVR1 mutations in FOP and DIPG: Opportunities and challenges in extending biological and clinical implications across rare diseases.

Overcoming resistance to single-agent therapy for oncogenic gene fusions combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.

The landscape of genomic alterations across childhood cancers.

Plain-language medical vocabulary for precision diagnosis.

Dual HDAC and PI3K Inhibition Abrogates NFκB- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas.

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.

Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation.

Author Correction: The landscape of genomic alterations across childhood cancers.

Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response.

Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy.

IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration.

A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.

Intratumoral Genetic and Functional Heterogeneity in Pediatric Glioblastoma.

Transcriptome signatures associated with meningioma progression.

Development and Clinical Validation of a Large Fusion Gene Panel for Pediatric Cancers.

Immunotherapy for pediatric brain tumors: past and present.

Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways.

Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer.

The InsP phosphatase Siw14 regulates inositol pyrophosphate levels to control localization of the general stress response transcription factor Msn2.

Ancestry and frequency of genetic variants in the general population are confounders in the characterization of germline variants linked to cancer.

A germline pathogenic variant identified in a pediatric high-grade glioma.

Harmonization of postmortem donations for pediatric brain tumors and molecular characterization of diffuse midline gliomas.

A transcriptome-based classifier to determine molecular subtypes in medulloblastoma.

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer.

annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions.

Genomic characterization of a PPP1CB-ALK fusion with fusion gene amplification in a congenital glioblastoma.

BRAF fusions in pediatric histiocytic neoplasms define distinct therapeutic responsiveness to RAF paradox breakers.

Proteogenomic and metabolomic characterization of human glioblastoma.

Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).

NTRK Fusions Identified in Pediatric Tumors: The Frequency, Fusion Partners, and Clinical Outcome.

Cancer Informatics for Cancer Centers: Scientific Drivers for Informatics, Data Science, and Care in Pediatric, Adolescent, and Young Adult Cancer.

Targeted gene expression profiling of inverted papilloma and squamous cell carcinoma.

MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data.

Neurotrophic tyrosine receptor kinase fusion in pediatric central nervous system tumors.

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.

The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.

ALT in Pediatric High-Grade Gliomas Can Occur without ATRX Mutation and is Enriched in Patients with Pathogenic Germline MMR Variants.