Howard Hughes Medical Institute and Program in Epithelial Biology
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Diversity, topographic differentiation, and positional memory in human fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12297622
Knowledge, attitudes, and practice styles of North American pediatric gastroenterologists: Helicobacter pylori infection.
Journal of pediatric gastroenterology and nutrition Feb, 2003 | Pubmed ID: 12548060
HOTAIR: Flight of noncoding RNAs in cancer metastasis.
Cell cycle (Georgetown, Tex.) Sep, 2010 | Pubmed ID: 20864820
Musings on the wanderer: what's new in our understanding of vago-vagal reflex? IV. Current concepts of vagal efferent projections to the gut.
American journal of physiology. Gastrointestinal and liver physiology Mar, 2003 | Pubmed ID: 12576302
Genomewide view of gene silencing by small interfering RNAs.
Proceedings of the National Academy of Sciences of the United States of America May, 2003 | Pubmed ID: 12730368
Myelogenous leukemia cutis resembling stasis dermatitis.
Journal of the American Academy of Dermatology Jul, 2003 | Pubmed ID: 12833025
Eruptive xanthomas associated with olanzapine use.
Archives of dermatology Aug, 2003 | Pubmed ID: 12925394
Endothelial cell diversity revealed by global expression profiling.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2003 | Pubmed ID: 12963823
Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.
PLoS biology Feb, 2004 | Pubmed ID: 14737219
Kinetics and specificity of fas ligand induction in toxic epidermal necrolysis.
Archives of dermatology Feb, 2004 | Pubmed ID: 14967808
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2005 | Pubmed ID: 15701700
The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62.
FEBS letters May, 2005 | Pubmed ID: 15878163
Learning more from microarrays: insights from modules and networks.
The Journal of investigative dermatology Aug, 2005 | Pubmed ID: 16098025
Genetic regulators of large-scale transcriptional signatures in cancer.
Nature genetics Apr, 2006 | Pubmed ID: 16518402
From description to causality: mechanisms of gene expression signatures in cancer.
Cell cycle (Georgetown, Tex.) Jun, 2006 | Pubmed ID: 16721055
MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species.
Cancer research Jul, 2006 | Pubmed ID: 16818632
Current gut-directed therapies for irritable bowel syndrome.
Current treatment options in gastroenterology Jul, 2006 | Pubmed ID: 16836950
Anatomic demarcation by positional variation in fibroblast gene expression programs.
PLoS genetics Jul, 2006 | Pubmed ID: 16895450
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17003113
Predicting a local recurrence after breast-conserving therapy by gene expression profiling.
Breast cancer research : BCR , 2006 | Pubmed ID: 17069664
Microarray analysis of stem cells and differentiation.
Methods in enzymology , 2006 | Pubmed ID: 17161699
Patterning skin pigmentation via dickkopf.
The Journal of investigative dermatology May, 2007 | Pubmed ID: 17435783
Decoding global gene expression programs in liver cancer by noninvasive imaging.
Nature biotechnology Jun, 2007 | Pubmed ID: 17515910
Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.
PLoS genetics Jun, 2007 | Pubmed ID: 17542650
A transcriptional program mediating entry into cellular quiescence.
PLoS genetics Jun, 2007 | Pubmed ID: 17559306
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs.
Cell Jun, 2007 | Pubmed ID: 17604720
Turning skin into embryonic stem cells.
Nature medicine Jul, 2007 | Pubmed ID: 17618266
A histone H3 lysine 27 demethylase regulates animal posterior development.
Nature Oct, 2007 | Pubmed ID: 17851529
Motif module map reveals enforcement of aging by continual NF-kappaB activity.
Genes & development Dec, 2007 | Pubmed ID: 18055696
Revealing targeted therapy for human cancer by gene module maps.
Cancer research Jan, 2008 | Pubmed ID: 18199530
CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression.
Cancer research Jan, 2008 | Pubmed ID: 18199546
A dermal HOX transcriptional program regulates site-specific epidermal fate.
Genes & development Feb, 2008 | Pubmed ID: 18245445
Systematic functional characterization of cis-regulatory motifs in human core promoters.
Genome research Mar, 2008 | Pubmed ID: 18256240
Reversal of aging by NFkappaB blockade.
Cell cycle (Georgetown, Tex.) Mar, 2008 | Pubmed ID: 18256548
A systems biology approach to anatomic diversity of skin.
The Journal of investigative dermatology Apr, 2008 | Pubmed ID: 18337710
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.
Nature Mar, 2008 | Pubmed ID: 18337721
Module map of stem cell genes guides creation of epithelial cancer stem cells.
Cell stem cell Apr, 2008 | Pubmed ID: 18397753
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.
The Journal of clinical investigation May, 2008 | Pubmed ID: 18414681
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3.
Genes & development Jul, 2008 | Pubmed ID: 18628393
Deletional tolerance mediated by extrathymic Aire-expressing cells.
Science (New York, N.Y.) Aug, 2008 | Pubmed ID: 18687966
Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification.
European journal of cancer (Oxford, England : 1990) Oct, 2008 | Pubmed ID: 18715778
Stemness, cancer and cancer stem cells.
Cell cycle (Georgetown, Tex.) Dec, 2008 | Pubmed ID: 19029796
Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes.
PloS one , 2008 | Pubmed ID: 19107207
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span.
Cell Jan, 2009 | Pubmed ID: 19135889
Molecular framework for response to imatinib mesylate in systemic sclerosis.
Arthritis and rheumatism Feb, 2009 | Pubmed ID: 19180499
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.
Molecular cell Jan, 2009 | Pubmed ID: 19187765
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.
Cell stem cell Feb, 2009 | Pubmed ID: 19200802
Genome-wide views of chromatin structure.
Annual review of biochemistry , 2009 | Pubmed ID: 19317649
Regeneration, repair and remembering identity: the three Rs of Hox gene expression.
Trends in cell biology Jun, 2009 | Pubmed ID: 19428253
Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression.
Cancer cell Jun, 2009 | Pubmed ID: 19477427
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.
Cancer cell Jun, 2009 | Pubmed ID: 19477431
Gene dates, parties and galas. Symposium on Chromatin Dynamics and Higher Order Organization.
EMBO reports Jul, 2009 | Pubmed ID: 19525922
HOXA3 modulates injury-induced mobilization and recruitment of bone marrow-derived cells.
Stem cells (Dayton, Ohio) Jul, 2009 | Pubmed ID: 19544454
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19666525
A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity.
The Journal of investigative dermatology Mar, 2010 | Pubmed ID: 19812599
Anatomic demarcation of cells: genes to patterns.
Science (New York, N.Y.) Nov, 2009 | Pubmed ID: 19965461
The histone demethylase UTX enables RB-dependent cell fate control.
Genes & development Feb, 2010 | Pubmed ID: 20123895
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Nature Apr, 2010 | Pubmed ID: 20393566
Tumor suppression by the histone demethylase UTX.
Cell cycle (Georgetown, Tex.) Jun, 2010 | Pubmed ID: 20505331
Long noncoding RNA as modular scaffold of histone modification complexes.
Science (New York, N.Y.) Aug, 2010 | Pubmed ID: 20616235
Genome-wide measurement of RNA secondary structure in yeast.
Nature Sep, 2010 | Pubmed ID: 20811459
Long noncoding RNA in genome regulation: prospects and mechanisms.
RNA biology Sep-Oct, 2010 | Pubmed ID: 20930520
G1 arrest and differentiation can occur independently of Rb family function.
The Journal of cell biology Nov, 2010 | Pubmed ID: 21059851
Opioid-induced bowel dysfunction.
Current treatment options in gastroenterology Feb, 2008 | Pubmed ID: 21063859
Noncoding RNA landmarks of pluripotency and reprogramming.
Cell stem cell Dec, 2010 | Pubmed ID: 21112559
Long intergenic noncoding RNAs: new links in cancer progression.
Cancer research Jan, 2011 | Pubmed ID: 21199792
RNA templating the epigenome: long noncoding RNAs as molecular scaffolds.
Epigenetics : official journal of the DNA Methylation Society May, 2011 | Pubmed ID: 21393997
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.
Nature Apr, 2011 | Pubmed ID: 21423168
Long noncoding RNAs and human disease.
Trends in cell biology Jun, 2011 | Pubmed ID: 21550244
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.
Nature genetics Jul, 2011 | Pubmed ID: 21642992
Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
EMBO reports Aug, 2011 | Pubmed ID: 21660059
Dynamic chromatin localization of Sirt6 shapes stress- and aging-related transcriptional networks.
PLoS genetics Jun, 2011 | Pubmed ID: 21738489
Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival.
The Journal of clinical investigation Sep, 2011 | Pubmed ID: 21821917
Understanding the transcriptome through RNA structure.
Nature reviews. Genetics Sep, 2011 | Pubmed ID: 21850044
Molecular mechanisms of long noncoding RNAs.
Molecular cell Sep, 2011 | Pubmed ID: 21925379
Direct lineage conversion of terminally differentiated hepatocytes to functional neurons.
Cell stem cell Oct, 2011 | Pubmed ID: 21962918
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions.
Molecular cell Nov, 2011 | Pubmed ID: 21963238
Active chromatin and noncoding RNAs: an intimate relationship.
Current opinion in genetics & development Dec, 2011 | Pubmed ID: 22154525
A Molecular Signature for Purified Definitive Endoderm Guides Differentiation and Isolation of Endoderm from Mouse and Human Embryonic Stem Cells.
Stem cells and development Feb, 2012 | Pubmed ID: 22236333
Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock.
Cell Jan, 2012 | Pubmed ID: 22265401
Suppression of progenitor differentiation requires the long noncoding RNA ANCR.
Genes & development Feb, 2012 | Pubmed ID: 22302877
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