Howard Y. Chang

Diversity, topographic differentiation, and positional memory in human fibroblasts.

Knowledge, attitudes, and practice styles of North American pediatric gastroenterologists: Helicobacter pylori infection.

HOTAIR: Flight of noncoding RNAs in cancer metastasis.

Musings on the wanderer: what's new in our understanding of vago-vagal reflex? IV. Current concepts of vagal efferent projections to the gut.

Genomewide view of gene silencing by small interfering RNAs.

Myelogenous leukemia cutis resembling stasis dermatitis.

Eruptive xanthomas associated with olanzapine use.

Endothelial cell diversity revealed by global expression profiling.

Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.

Kinetics and specificity of fas ligand induction in toxic epidermal necrolysis.

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival.

The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62.

Learning more from microarrays: insights from modules and networks.

Genetic regulators of large-scale transcriptional signatures in cancer.

From description to causality: mechanisms of gene expression signatures in cancer.

MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species.

Current gut-directed therapies for irritable bowel syndrome.

Anatomic demarcation by positional variation in fibroblast gene expression programs.

Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation.

Predicting a local recurrence after breast-conserving therapy by gene expression profiling.

Microarray analysis of stem cells and differentiation.

Patterning skin pigmentation via dickkopf.

Decoding global gene expression programs in liver cancer by noninvasive imaging.

Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.

A transcriptional program mediating entry into cellular quiescence.

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs.

Turning skin into embryonic stem cells.

A histone H3 lysine 27 demethylase regulates animal posterior development.

Motif module map reveals enforcement of aging by continual NF-kappaB activity.

Revealing targeted therapy for human cancer by gene module maps.

CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression.

A dermal HOX transcriptional program regulates site-specific epidermal fate.

Systematic functional characterization of cis-regulatory motifs in human core promoters.

Reversal of aging by NFkappaB blockade.

A systems biology approach to anatomic diversity of skin.

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.

Module map of stem cell genes guides creation of epithelial cancer stem cells.

Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.

Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3.

Deletional tolerance mediated by extrathymic Aire-expressing cells.

Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification.

Stemness, cancer and cancer stem cells.

Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes.

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span.

Molecular framework for response to imatinib mesylate in systemic sclerosis.

ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.

Genome-wide views of chromatin structure.

Regeneration, repair and remembering identity: the three Rs of Hox gene expression.

Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression.

Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.

Gene dates, parties and galas. Symposium on Chromatin Dynamics and Higher Order Organization.

HOXA3 modulates injury-induced mobilization and recruitment of bone marrow-derived cells.

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells.

A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity.

Anatomic demarcation of cells: genes to patterns.

The histone demethylase UTX enables RB-dependent cell fate control.

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.

Tumor suppression by the histone demethylase UTX.

Long noncoding RNA as modular scaffold of histone modification complexes.

Genome-wide measurement of RNA secondary structure in yeast.

Long noncoding RNA in genome regulation: prospects and mechanisms.

G1 arrest and differentiation can occur independently of Rb family function.

Opioid-induced bowel dysfunction.

Noncoding RNA landmarks of pluripotency and reprogramming.

Long intergenic noncoding RNAs: new links in cancer progression.

RNA templating the epigenome: long noncoding RNAs as molecular scaffolds.

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.

Long noncoding RNAs and human disease.

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.

Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.

Dynamic chromatin localization of Sirt6 shapes stress- and aging-related transcriptional networks.

Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival.

Understanding the transcriptome through RNA structure.

Molecular mechanisms of long noncoding RNAs.

Direct lineage conversion of terminally differentiated hepatocytes to functional neurons.

Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions.

Active chromatin and noncoding RNAs: an intimate relationship.

A Molecular Signature for Purified Definitive Endoderm Guides Differentiation and Isolation of Endoderm from Mouse and Human Embryonic Stem Cells.

Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock.

Suppression of progenitor differentiation requires the long noncoding RNA ANCR.