Karen Ocorr

The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman.

Age-related cardiac disease model of Drosophila.

KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.

Genetic control of heart function and aging in Drosophila.

Genetic variation for cardiac dysfunction in Drosophila.

ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway.

Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles.

Drosophila aging 2006/2007.

The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function.

ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway.

Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype.

A novel human BTB-kelch protein KLHL31, strongly expressed in muscle and heart, inhibits transcriptional activities of TRE and SRE.

Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease.

Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies.

A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts.

d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.

Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner.

Drug discovery through functional screening in the Drosophila heart.

KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1.

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.

The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development.

SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity.

High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila.

Drosophila as a model to study cardiac aging.

Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila.

Cloning and characterization of the cardiac-specific Lrrc10 promoter.

Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species.

ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections.

The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.

Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects.

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.