Development and Aging Program,
NASCR Center,
Development and Aging Program, NASCR Center
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The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2006 | Pubmed ID: 16882722
Age-related cardiac disease model of Drosophila.
Mechanisms of ageing and development Jan, 2007 | Pubmed ID: 17125816
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2007 | Pubmed ID: 17360457
Genetic control of heart function and aging in Drosophila.
Trends in cardiovascular medicine Jul, 2007 | Pubmed ID: 17574126
Genetic variation for cardiac dysfunction in Drosophila.
PloS one , 2007 | Pubmed ID: 17622346
ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway.
Biochemical and biophysical research communications Nov, 2007 | Pubmed ID: 17910948
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles.
Molecular biology of the cell Feb, 2008 | Pubmed ID: 18045988
Drosophila aging 2006/2007.
Experimental gerontology Jan, 2008 | Pubmed ID: 18061385
The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function.
The Journal of experimental biology Jan, 2008 | Pubmed ID: 18083727
ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway.
Molecular and cellular biochemistry Mar, 2008 | Pubmed ID: 18084723
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype.
Aging cell Mar, 2008 | Pubmed ID: 18221418
A novel human BTB-kelch protein KLHL31, strongly expressed in muscle and heart, inhibits transcriptional activities of TRE and SRE.
Molecules and cells Nov, 2008 | Pubmed ID: 18719355
Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2008 | Pubmed ID: 19074289
Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies.
Developmental biology Apr, 2009 | Pubmed ID: 19233157
A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts.
BioTechniques Feb, 2009 | Pubmed ID: 19317655
d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.
Aging cell Sep, 2009 | Pubmed ID: 19594484
Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner.
PloS one , 2009 | Pubmed ID: 19718456
Drug discovery through functional screening in the Drosophila heart.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19718521
KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1.
BMB reports Jan, 2010 | Pubmed ID: 20132730
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.
Science (New York, N.Y.) Mar, 2010 | Pubmed ID: 20203043
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
Cell Apr, 2010 | Pubmed ID: 20371351
The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development.
Molecular biology reports Feb, 2011 | Pubmed ID: 20383585
SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity.
BMB reports May, 2010 | Pubmed ID: 20510020
High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila.
Cell metabolism Nov, 2010 | Pubmed ID: 21035763
Drosophila as a model to study cardiac aging.
Experimental gerontology May, 2011 | Pubmed ID: 21130861
Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila.
Genes & development Jan, 2011 | Pubmed ID: 21245170
Cloning and characterization of the cardiac-specific Lrrc10 promoter.
BMB reports Feb, 2011 | Pubmed ID: 21345312
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species.
The Journal of cell biology Jun, 2011 | Pubmed ID: 21690310
ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2011 | Pubmed ID: 21719711
The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.
PloS one , 2011 | Pubmed ID: 21799905
Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects.
PLoS genetics Nov, 2011 | Pubmed ID: 22072978
BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.
Heart rhythm : the official journal of the Heart Rhythm Society Dec, 2011 | Pubmed ID: 22138472
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