Gerhard Schuler

Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemic syndromes: results of 3 randomized studies.

Improvement of peripheral endothelial dysfunction by acute vitamin C application: different effects in patients with coronary artery disease, ischemic, and dilated cardiomyopathy.

Promoter but not exon 7 polymorphism of endothelial nitric oxide synthase affects training-induced correction of endothelial dysfunction.

Short- and long-term hemodynamic effects of intra-aortic balloon support in ventricular septal defect complicating acute myocardial infarction.

Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure.

Nuclear factor-kappa B activation in skeletal muscle of patients with chronic heart failure: correlation with the expression of inducible nitric oxide synthase.

Differential gene expression in skeletal muscle after induction of heart failure: impact of cytokines on protein phosphatase 2A expression.

Invasive assessment of bacterial endotoxin and inflammatory cytokines in patients with acute heart failure.

Exercise training in patients with severe chronic heart failure: impact on left ventricular performance and cardiac size. A retrospective analysis of the Leipzig Heart Failure Training Trial.

Contemporary outcome of cardiac catheterizations in 1085 consecutive octogenarians.

Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia.

Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery disease: a randomized trial.

Polymer-sirolimus-eluting stents in de novo lesions.

Comparison of early and late results of a Carbofilm-coated stent versus a pure high-grade stainless steel stent (the Carbostent-Trial).

Functional and morphological skeletal muscle abnormalities correlate with reduced electromyographic activity in chronic heart failure.

[Lifelong after-care and secondary prevention after myocardial infarct].

[Hypertension and exercise. Sports methods for the hypertensive patient].

Impact of diabetes mellitus type 2 on in-hospital outcome after cardiac catheterizations in a large cohort of octogenarians.

Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins: comparison with surgical and percutaneous intramyocardial gene delivery.

Effectiveness and safety of the Proxis system in demonstrating retrograde coronary blood flow during proximal occlusion and in capturing embolic material.

Effect of two different neuroprotection systems on microembolization during carotid artery stenting.

Hyperglycemia reduces survival and impairs function of circulating blood-derived progenitor cells.

Impact of regular physical activity on the NAD(P)H oxidase and angiotensin receptor system in patients with coronary artery disease.

Maintenance of long-term clinical benefit with sirolimus-eluting coronary stents: three-year results of the RAVEL trial.

Randomized comparison of intra-aortic balloon support with a percutaneous left ventricular assist device in patients with revascularized acute myocardial infarction complicated by cardiogenic shock.

Color-encoded semiautomatic analysis of multi-slice first-pass magnetic resonance perfusion: comparison to tetrofosmin single photon emission computed tomography perfusion and X-ray angiography.

Changes in myocardial perfusion due to physical exercise in patients with stable coronary artery disease.

Antioxidative effects of exercise training in patients with chronic heart failure: increase in radical scavenger enzyme activity in skeletal muscle.

Proximal endovascular flow blockage for cerebral protection during carotid artery stenting: results from a prospective multicenter registry.

Therapeutical potential of blood-derived progenitor cells in patients with peripheral arterial occlusive disease and critical limb ischaemia.

Prospective randomized comparison of early and late results of a carbonized stent versus a high-grade stainless steel stent of identical design: the PREVENT Trial [corrected].

Comparison of pre-hospital combination-fibrinolysis plus conventional care with pre-hospital combination-fibrinolysis plus facilitated percutaneous coronary intervention in acute myocardial infarction.

Exercise training in chronic heart failure: correlation between reduced local inflammation and improved oxidative capacity in the skeletal muscle.

Effects of exercise training on insulin-like growth factor-I expression in the skeletal muscle of non-cachectic patients with chronic heart failure.

Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study.

Aging and heart failure--similar syndromes of exercise intolerance? Implications for exercise-based interventions.

Magnetic resonance imaging after percutaneous closure of a ventricular septal defect complicating myocardial infarction.

Comparison of bare-metal stenting with minimally invasive bypass surgery for stenosis of the left anterior descending coronary artery: a 5-year follow-up.

Anti-inflammatory effects of physical exercise. A new mechanism to explain the benefits of cardiac rehabilitation?

Correlation of exercise capacity with high-sensitive C-reactive protein in patients with stable coronary artery disease.

Implications of exercise test modality on modern prognostic markers in patients with known or suspected coronary artery disease: treadmill versus bicycle.

Expression of cyclooxygenase 1 and 2 in the canine corpus luteum during diestrus.

[Germany's girths in an international comparison].

Intracoronary administration of circulating blood-derived progenitor cells after recanalization of chronic coronary artery occlusion improves endothelial function.

Transapical approach for sutureless stent-fixed aortic valve implantation: experimental results.

Reproducibility of chronic and acute infarct size measurement by delayed enhancement-magnetic resonance imaging.

Incidence, time course, and predictors of early malignant ventricular arrhythmias after non-ST-segment elevation myocardial infarction in patients with early invasive treatment.

Transapical aortic valve implantation: an animal feasibility study.

Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: the EPAS trial.

Both T-786C and G894T polymorphism of endothelial nitric oxide synthase affect in-vitro endothelium-dependent relaxation of internal mammary artery rings from patients with coronary artery disease.

ST-segment recovery and prognosis in patients with ST-elevation myocardial infarction reperfused by prehospital combination fibrinolysis, prehospital initiated facilitated percutaneous coronary intervention, or primary percutaneous coronary intervention.

Minimally invasive transapical beating heart aortic valve implantation--proof of concept.

Myocardial expression of Murf-1 and MAFbx after induction of chronic heart failure: Effect on myocardial contractility.

[Acute heart failure: rational diagnostics in clinical practice and the emergency department].

Initial worldwide experience with the WATCHMAN left atrial appendage system for stroke prevention in atrial fibrillation.

Influence of time-to-treatment, TIMI-flow grades, and ST-segment resolution on infarct size and infarct transmurality as assessed by delayed enhancement magnetic resonance imaging.

High, but not moderate frequency and duration of exercise training induces downregulation of the expression of inflammatory and atherogenic adhesion molecules.

Percutaneous left ventricular assist devices in acute myocardial infarction complicated by cardiogenic shock.

Valve-in-a-valve concept for transcatheter minimally invasive repeat xenograft implantation.

Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome.

Restoration of microvascular function in the infarct-related artery by intracoronary transplantation of bone marrow progenitor cells in patients with acute myocardial infarction: the Doppler Substudy of the Reinfusion of Enriched Progenitor Cells and Infarct Remodeling in Acute Myocardial Infarction (REPAIR-AMI) trial.

Complete occlusion of the aortic isthmus.

Transapical minimally invasive aortic valve implantation: multicenter experience.

A tetraantennary glycan with bisecting N-acetylglucosamine and the Sd(a) antigen is the predominant N-glycan on bovine pregnancy-associated glycoproteins.

Impact of physical exercise on alterations in the skeletal muscle in patients with chronic heart failure.

Interventional treatments for stroke prevention in atrial fibrillation with emphasis upon the WATCHMAN device.

Delayed enhancement magnetic resonance imaging in isolated noncompaction of ventricular myocardium.

Regular exercise training compared with percutaneous intervention leads to a reduction of inflammatory markers and cardiovascular events in patients with coronary artery disease.

ASD and PFO closure with the Solysafe septal occluder - results of a prospective multicenter pilot study.

Human minimally invasive off-pump valve-in-a-valve implantation.

Transapical minimally invasive aortic valve implantation; the initial 50 patients.

Effect of progenitor cells on myocardial perfusion and metabolism in patients after recanalization of a chronically occluded coronary artery.

Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.

[Conservative treatment of coronary heart disease--current options].

Prognostic significance and magnetic resonance imaging findings in aborted myocardial infarction after primary angioplasty.

Depressed expression of MuRF1 and MAFbx in areas remote of recent myocardial infarction: a mechanism contributing to myocardial remodeling?

Modulation of Murf-1 and MAFbx expression in the myocardium by physical exercise training.

Intracoronary compared with intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: the randomized Leipzig immediate percutaneous coronary intervention abciximab IV versus IC in ST-elevation myocardial infarction trial.

Minimally invasive off-pump valve-in-a-valve implantation: the atrial transcatheter approach for re-operative mitral valve replacement.

Frequency and pattern of de-novo three-vessel and left main coronary artery disease; insights from single center enrolment in the SYNTAX study.

Cardiac magnetic resonance imaging at 3 and 15 months after application of circulating progenitor cells in recanalised chronic total occlusions.

Takotsubo cardiomyopathy or myocardial infarction? Answers from delayed enhancement magnetic resonance imaging.

Covered rupture of the free left ventricular wall or "only" thrombus in a true aneurysm?

Increasing physical education in high school students: effects on concentration of circulating endothelial progenitor cells.

Exercise training but not rosiglitazone improves endothelial function in prediabetic patients with coronary disease.

Commentary on Viewpoint: Exercise and cardiovascular risk reduction: time to update the rationale for exercise?

Circulating progenitor cells decrease immediately after marathon race in advanced-age marathon runners.

Induction of MuRF1 is essential for TNF-alpha-induced loss of muscle function in mice.

Differential diagnosis of suspected apical ballooning syndrome using contrast-enhanced magnetic resonance imaging.

Endothelial progenitor cells: implications for cardiovascular disease.

Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: a novel concept for valvular endothelial cell repair.

Immediate primary transcatheter closure of postinfarction ventricular septal defects.

Minimally invasive off-pump aortic valve implantation: the surgical safety net.

Transapical aortic valve implantation: step by step.

Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.

Full recovery of Takotsubo cardiomyopathy (apical ballooning) in two days.

Cardiogenic shock: to pump or not to pump?

Impact of exercise training on myostatin expression in the myocardium and skeletal muscle in a chronic heart failure model.

New anatomically oriented transapical aortic valve implantation.

Anesthesia management for transapical transcatheter aortic valve implantation: a case series.

Endocrine changes during pregnancy, parturition and post-partum in guanacos (Lama guanicoe).

Transapical aortic valve implantation in patients requiring redo surgery.

Reduced-dose fibrinolytic acceleration of ST-segment elevation myocardial infarction treatment coupled with urgent percutaneous coronary intervention compared to primary percutaneous coronary intervention alone results of the AMICO (Alliance for Myocardial Infarction Care Optimization) Registry.

Randomized comparison of minimally invasive direct coronary artery bypass surgery versus sirolimus-eluting stenting in isolated proximal left anterior descending coronary artery stenosis.

Myocarditis mimicking Takotsubo cardiomyopathy or Takotsubo cardiomyopathy with secondary inflammation?

Haemodynamic effects, safety, and tolerability of haemoglobin-based oxygen carrier-201 in patients undergoing PCI for CAD.

Risk factor management: antiatherogenic therapies.

Basic and translational research: from molecule, to mouse, to man.

Awake transapical aortic valve implantation using thoracic epidural anesthesia.

Inflammation in takotsubo cardiomyopathy: insights from cardiovascular magnetic resonance imaging.

ST-segment resolution and prognosis after facilitated versus primary percutaneous coronary intervention in acute myocardial infarction: a meta-analysis.

Left ventricular assist devices in cardiogenic shock and high-risk PCI.

Randomised comparison of Nobori, biolimus A9-eluting coronary stent with a Taxus(R), paclitaxel-eluting coronary stent in patients with stenosis in native coronary arteries: the Nobori 1 trial.

Transcatheter aortic valve implantation: review of the nature, management, and avoidance of procedural complications.

Long- but not short-term multifactorial intervention with focus on exercise training improves coronary endothelial dysfunction in diabetes mellitus type 2 and coronary artery disease.

Time-dependent mobilization of circulating progenitor cells during strenuous exercise in healthy individuals.

Endocardial calcification of left atrium, tracheobronchopathia osteoplastica, and calcified aortic arch in a patient with dyspnea.

Effect of coronary collaterals on microvascular obstruction as assessed by magnetic resonance imaging in patients with acute ST-elevation myocardial infarction treated by primary coronary intervention.

Effect of cocoa products on blood pressure: systematic review and meta-analysis.

Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trial.

Dyna-CT during minimally invasive off-pump transapical aortic valve implantation.

Ovarian follicular dynamics and hormonal secretory profiles in guanacos (Lama guanicoe).

Ingrowths of a percutaneously implanted aortic valve prosthesis (corevalve) in a patient with severe aortic stenosis.

Randomized comparison of the Nobori Biolimus A9-eluting coronary stent with the Taxus Liberté paclitaxel-eluting coronary stent in patients with stenosis in native coronary arteries: the NOBORI 1 trial--Phase 2.

ANRIL expression is associated with atherosclerosis risk at chromosome 9p21.

The utility of trans-catheter aortic valve replacement after commercialization: does the European experience provide a glimpse into the future use of this technology in the United States?

Regular exercise training prevents aortic valve disease in low-density lipoprotein-receptor-deficient mice.

A clinical protocol for analysis of the structural integrity of the Medtronic CoreValve System frame and its application in patients with 1-year minimum follow-up.

Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients.

Transapical aortic valve implantation in 100 consecutive patients: comparison to propensity-matched conventional aortic valve replacement.

High-dose rosuvastatin in chronic heart failure promotes vasculogenesis, corrects endothelial function, and improves cardiac remodeling--results from a randomized, double-blind, and placebo-controlled study.

Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention: design and rationale of the Abciximab Intracoronary versus intravenously Drug Application in ST-Elevation Myocardial Infarction (AIDA STEMI) trial.

[Coronary artery bypass surgery for the treatment of acute coronary syndromes].

How to improve endothelial repair mechanisms: the lifestyle approach.

Prevalence and functional impact of lipomatous metaplasia in scar tissue following myocardial infarction evaluated by MRI.

Exercise training in patients with advanced chronic heart failure (NYHA IIIb) promotes restoration of peripheral vasomotor function, induction of endogenous regeneration, and improvement of left ventricular function.

Endothelin-1 release in acute myocardial infarction as a predictor of long-term prognosis and no-reflow assessed by contrast-enhanced magnetic resonance imaging.

Latest advances in transcatheter aortic valve implantation.

Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The LIPSIA-N-ACC (Prospective, Single-Blind, Placebo-Controlled, Randomized Leipzig Immediate PercutaneouS Coronary Intervention Acute Myocardial Infarction N-ACC) Trial.

Transapical off-pump valve-in-valve implantation in patients with degenerated aortic xenografts.

Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction.

Biventricular stress-induced (takotsubo) cardiomyopathy with left midventricular and right apical ballooning.

Maximal exercise, limb ischemia, and endothelial progenitor cells.

Shock in acute myocardial infarction: the Cape Horn for trials?

Use of the progesterone (P4) receptor antagonist aglepristone to characterize the role of P4 withdrawal for parturition and placental release in cows.

One-year interim follow-up results of the TRAVERCE trial: the initial feasibility study for trans-apical aortic-valve implantation.

Impact of early vs. late microvascular obstruction assessed by magnetic resonance imaging on long-term outcome after ST-elevation myocardial infarction: a comparison with traditional prognostic markers.

Effect of coronary collaterals on long-term prognosis in patients undergoing primary angioplasty for acute ST-elevation myocardial infarction.

Timing of invasive treatment after fibrinolysis in ST elevation myocardial infarction--a meta-analysis of immediate or early routine versus deferred or ischemia-guided randomised controlled trials.

Aborted myocardial infarction in intracoronary compared with standard intravenous abciximab administration in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.

Cardiovascular effects of exercise training: molecular mechanisms.

Transapical aortic valve implantation: therapy of choice for patients with aortic stenosis and porcelain aorta?

Impact of minimising door-to-balloon times in ST-elevation myocardial infarction to less than 30 min on outcome: an analysis over an 8-year period in a tertiary care centre.

Endothelial progenitor cells and exercise-induced redox regulation.

Intracoronary versus intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: 6-month effects on infarct size and left ventricular function. The randomised Leipzig Immediate PercutaneouS Coronary Intervention Abciximab i.v. versus i.c. in ST-Elevation Myocardial Infarction Trial (LIPSIAbciximab-STEMI).

Effects of age and altrenogest treatment on conceptus development and secretion of LH, progesterone and eCG in early-pregnant mares.

Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevation myocardial infarction and early invasive treatment strategy.

Risk of acute kidney injury after minimally invasive transapical aortic valve implantation in 270 patients.

Randomized comparison of percutaneous coronary intervention with sirolimus-eluting stents versus coronary artery bypass grafting in unprotected left main stem stenosis.

Reliability of myocardial salvage assessment by cardiac magnetic resonance imaging in acute reperfused myocardial infarction.

Growth-differentiation factor 15 as predictor of mortality in acute reperfused ST-elevation myocardial infarction: insights from cardiovascular magnetic resonance.

Role of endothelial progenitor cells in the beneficial effects of physical exercise on atherosclerosis and coronary artery disease.

Randomized clinical trial comparing percutaneous closure of patent foramen ovale (PFO) using the Amplatzer PFO Occluder with medical treatment in patients with cryptogenic embolism (PC-Trial): rationale and design.

New familial heterozygous c 4066_4068 delTT 2 bp deletion of the SCN5A gene causing Brugada syndrome.

Aortic regurgitation after transcatheter aortic valve implantation: incidence and early outcome. Results from the German transcatheter aortic valve interventions registry.

Prevalence and clinical impact of left coronary dominance in patients with aortic stenosis.

Testosterone replacement effectively inhibits the development of experimental autoimmune orchitis in rats: evidence for a direct role of testosterone on regulatory T cell expansion.

Exercise training restores the endothelial response to vascular growth factors in patients with stable coronary artery disease.

Exercise training leads to a reduction of elevated myostatin levels in patients with chronic heart failure.

Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training.

2-year follow-up of patients undergoing transcatheter aortic valve implantation using a self-expanding valve prosthesis.

Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial.

Prognostic value and determinants of a hypointense infarct core in T2-weighted cardiac magnetic resonance in acute reperfused ST-elevation-myocardial infarction.

A second prosthesis as a procedural rescue option in trans-apical aortic valve implantation.

Effect of carotid artery stenting on the release of S-100B and neurone-specific enolase.

Randomized comparison of pre-hospital-initiated facilitated percutaneous coronary intervention versus primary percutaneous coronary intervention in acute myocardial infarction very early after symptom onset: the LIPSIA-STEMI trial (Leipzig immediate prehospital facilitated angioplasty in ST-segment myocardial infarction).

Impact of N-acetylcysteine on contrast-induced nephropathy defined by cystatin C in patients with ST-elevation myocardial infarction undergoing primary angioplasty.

Transapical aortic valve implantation at 3 years.

Clinical characteristics and cardiovascular magnetic resonance findings in stress (takotsubo) cardiomyopathy.

Transapical aortic valve implantation: analysis of risk factors and learning experience in 299 patients.

Cardiac magnetic resonance imaging parameters as surrogate endpoints in clinical trials of acute myocardial infarction.

Myocardium at risk in ST-segment elevation myocardial infarction comparison of T2-weighted edema imaging with the MR-assessed endocardial surface area and validation against angiographic scoring.

Trans-apical aortic valve implantation using a new self-expandable bioprosthesis: initial outcomes.

Coronary artery disease and aortic stenosis: small steps to cross the border to full interventional treatment in selected high-risk patients.

Tools & techniques: Percutaneous left ventricular assist devices.

Muscle metabolism and exercise capacity in cachexia.

[Conservative management of coronary artery disease].

Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction.

Platelet inhibition and GP IIb/IIIa receptor occupancy by intracoronary versus intravenous bolus administration of abciximab in patients with ST-elevation myocardial infarction.

Sex differences in myocardial salvage and clinical outcome in patients with acute reperfused ST-elevation myocardial infarction: advances in cardiovascular imaging.

Time-dependency, predictors and clinical impact of infarct transmurality assessed by magnetic resonance imaging in patients with ST-elevation myocardial infarction reperfused by primary coronary percutaneous intervention.

Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig Immediate versus early and late PercutaneouS coronary Intervention triAl in NSTEMI (LIPSIA-NSTEMI Trial).

Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilege.

Rationale and design of the Leipzig (LIFE) Heart Study: phenotyping and cardiovascular characteristics of patients with coronary artery disease.

The Leipzig prospective vascular ultrasound registry in radial artery catheterization: impact of sheath size on vascular complications.

Age-related effects of exercise training on diastolic function in heart failure with reduced ejection fraction: The Leipzig Exercise Intervention in Chronic Heart Failure and Aging (LEICA) Diastolic Dysfunction Study.

Relationship and prognostic value of microvascular obstruction and infarct size in ST-elevation myocardial infarction as visualized by magnetic resonance imaging.

Transapical double valve implantation plus percutaneous revascularization as a bailout for a high-risk patient.

Short- and mid-term safety and effectiveness of transcatheter aortic valve implantation in a failing surgical aortic bioprosthesis.

Intracoronary versus intravenous bolus abciximab during primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction: a randomised trial.