Clayton Foundation Laboratories for Peptide Biology
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Evidence for a centrally located gate in the pore of a serotonin-gated ion channel.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2002 | Pubmed ID: 11880493
betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation.
The Journal of physiology Mar, 2004 | Pubmed ID: 14724209
Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system.
Nature neuroscience Feb, 2004 | Pubmed ID: 14745451
Minimal structural rearrangement of the cytoplasmic pore during activation of the 5-HT3A receptor.
The Journal of biological chemistry Jul, 2004 | Pubmed ID: 15131114
Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex.
Molecular and cellular neurosciences Feb, 2005 | Pubmed ID: 15691717
Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification.
Nature neuroscience Mar, 2005 | Pubmed ID: 15723059
Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells.
Pflügers Archiv : European journal of physiology Apr, 2005 | Pubmed ID: 15806402
Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1.
Biochemistry Jul, 2006 | Pubmed ID: 16834334
Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.
The Journal of physiology Apr, 2007 | Pubmed ID: 17185339
NMR studies of interactions between C-terminal tail of Kir2.1 channel and PDZ1,2 domains of PSD95.
Biochemistry May, 2007 | Pubmed ID: 17437338
Coregulation of natively expressed pertussis toxin-sensitive muscarinic receptors with G-protein-activated potassium channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2007 | Pubmed ID: 17567799
Genetically encoding unnatural amino acids for cellular and neuronal studies.
Nature neuroscience Aug, 2007 | Pubmed ID: 17603477
The role of the cytoplasmic pore in inward rectification of Kir2.1 channels.
The Journal of general physiology Aug, 2007 | Pubmed ID: 17635958
A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction.
Nature neuroscience Oct, 2007 | Pubmed ID: 17828261
RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area.
Nature neuroscience Dec, 2007 | Pubmed ID: 17965710
Subunit-specific regulation of Kir3 channels by sorting nexin 27.
Channels (Austin, Tex.) Sep-Oct, 2007 | Pubmed ID: 18690037
Addictive drugs modulate GIRK-channel signaling by regulating RGS proteins.
Trends in pharmacological sciences Nov, 2008 | Pubmed ID: 18790542
Regulation of Kir2.1 channels by the Rho-GTPase, Rac1.
Journal of cellular physiology Feb, 2009 | Pubmed ID: 18932198
A discrete alcohol pocket involved in GIRK channel activation.
Nature neuroscience Aug, 2009 | Pubmed ID: 19561601
Direct interaction of GABAB receptors with M2 muscarinic receptors enhances muscarinic signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2009 | Pubmed ID: 20016095
Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.
Nature reviews. Neuroscience May, 2010 | Pubmed ID: 20389305
GABAB receptor coupling to G-proteins and ion channels.
Advances in pharmacology (San Diego, Calif.) , 2010 | Pubmed ID: 20655481
Basal GABA regulates GABA(B)R conformation and release probability at single hippocampal synapses.
Neuron Jul, 2010 | Pubmed ID: 20670833
Probing novel GPCR interactions using a combination of FRET and TIRF.
Communicative & integrative biology Jul, 2010 | Pubmed ID: 20798821
Morphine- and CaMKII-dependent enhancement of GIRK channel signaling in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2010 | Pubmed ID: 20926668
Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2011 | Pubmed ID: 21422294
Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution.
Alcoholism, clinical and experimental research Sep, 2011 | Pubmed ID: 21676006
Compartmentalization of the GABAB receptor signaling complex is required for presynaptic inhibition at hippocampal synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2011 | Pubmed ID: 21880914
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