Assessing Antibody-dependent, Cell-mediated Cytotoxicity in Cancer Cells using Antibody-Dependent Cell-Mediated Cytotoxicity Reporter BioassayKelvin Kam Yew Kuan *1, Ke Zhang *1,2, Koon Hwee Ang 1, Min Thura 1, Wei Hui Zheng 3,4
1Institute of Molecular and Cell Biology (IMCB), A*STAR 61 Biopolis Drive, 2Department of Radiation Oncology, Affiliated Hangzhou Cancer Hospital, 3Key Laboratory of Head and Neck Cancer Translational Research of Zhejiang Province, Zhejiang Cancer Hospital, 4Department of Thyroid Surgery of Zhejiang Cancer Hospital
Here, we present a protocol for an antibody-dependent, cell-mediated cytotoxicity (ADCC) assay using an ADCC bioassay kit. This method offers a valuable tool for elucidating the ADCC mechanism and evaluating the therapeutic potential of antibodies in cancer immunotherapy.
