Fox Chase Cancer Center
3 ARTICLES PUBLISHED IN JoVE
Medicine
An in vivo Assay to Test Blood Vessel Permeability
Maria Radu 1, Jonathan Chernoff 1
1Fox Chase Cancer Center
We are presenting an in vivo assay to test blood vessel permeability. This assay is based on intravenous injection of a dye and subsequent visualization of its diffusion into interstitial spaces.
Medicine
Minimal Erythema Dose (MED) Testing
Carolyn J. Heckman 1, Rachel Chandler 2, Jacqueline D. Kloss 3, Amy Benson 2, Deborah Rooney 2, Teja Munshi 1, Susan D. Darlow 1, Clifford Perlis 4, Sharon L. Manne 5, David W. Oslin 2
1Cancer Prevention and Control Program, Fox Chase Cancer Center , 2Department of Psychiatry, University of Pennsylvania , 3Department of Psychology, Drexel University , 4Department of Medicine, Fox Chase Cancer Center , 5Cancer Prevention and Control Program, The Cancer Institute of New Jersey
This article describes how to conduct minimal erythema dose (MED) testing in order to determine the lowest dose of ultraviolet radiation that will cause erythema (burning) when administered to an individual.
Biochemistry
Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay
Sofiia Karchugina 1, Jonathan Chernoff 1
1Fox Chase Cancer Center
Here, we show how to use a Proximity Ligation Assay (PLA) to visualize MST1/MST2 heterodimerization in fixed cells with high sensitivity.
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