Isaac Edery

Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity.

Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.

A role for CK2 in the Drosophila circadian oscillator.

Splicing of the period gene 3'-terminal intron is regulated by light, circadian clock factors, and phospholipase C.

Analyzing the degradation of PERIOD protein by the ubiquitin-proteasome pathway in cultured Drosophila cells.

Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein.

Clock-gated photic stimulation of timeless expression at cold temperatures and seasonal adaptation in Drosophila.

Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from Drosophila.

A blend of two circadian clocks, seasoned to perfection.

A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function.

Cis-combination of the classic per(S) and per(L) mutations results in arrhythmic Drosophila with ectopic accumulation of hyperphosphorylated PERIOD protein.

Circadian regulation in the ability of Drosophila to combat pathogenic infections.

Circadian regulation of a limited set of conserved microRNAs in Drosophila.

The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.

Natural variation in the splice site strength of a clock gene and species-specific thermal adaptation.

A stretch from the periphery helps brain clocks feel the daily heat.

A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.

Circadian rhythms. Temperatures to communicate by.

Two distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription.

NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed.

A master CLOCK hard at work brings rhythm to the transcriptome.

A morning-induced, phosphorylation-gated repressor times evening gene expression: a new way for circadian clocks to use an old trick.

A role for O-GlcNAcylation in setting circadian clock speed.