Center for Advanced Biotechnology and Medicine,
Department of Molecular Biology and Biochemistry
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Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity.
Neuron Mar, 2002 | Pubmed ID: 11931742
Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.
Nature Dec, 2002 | Pubmed ID: 12442174
A role for CK2 in the Drosophila circadian oscillator.
Nature neuroscience Mar, 2003 | Pubmed ID: 12563262
Splicing of the period gene 3'-terminal intron is regulated by light, circadian clock factors, and phospholipase C.
Molecular and cellular biology Apr, 2004 | Pubmed ID: 15060157
Analyzing the degradation of PERIOD protein by the ubiquitin-proteasome pathway in cultured Drosophila cells.
Methods in enzymology , 2005 | Pubmed ID: 15817301
Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2006 | Pubmed ID: 16603629
Clock-gated photic stimulation of timeless expression at cold temperatures and seasonal adaptation in Drosophila.
Journal of biological rhythms Aug, 2006 | Pubmed ID: 16864646
Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from Drosophila.
Journal of biochemistry Nov, 2006 | Pubmed ID: 17012288
A blend of two circadian clocks, seasoned to perfection.
Cell Apr, 2007 | Pubmed ID: 17418778
A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function.
Molecular and cellular biology Jul, 2007 | Pubmed ID: 17452449
Cis-combination of the classic per(S) and per(L) mutations results in arrhythmic Drosophila with ectopic accumulation of hyperphosphorylated PERIOD protein.
Journal of biological rhythms Dec, 2007 | Pubmed ID: 18057324
Circadian regulation in the ability of Drosophila to combat pathogenic infections.
Current biology : CB Feb, 2008 | Pubmed ID: 18261909
Circadian regulation of a limited set of conserved microRNAs in Drosophila.
BMC genomics , 2008 | Pubmed ID: 18284684
The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.
Genes & development Jul, 2008 | Pubmed ID: 18593878
Natural variation in the splice site strength of a clock gene and species-specific thermal adaptation.
Neuron Dec, 2008 | Pubmed ID: 19109911
A stretch from the periphery helps brain clocks feel the daily heat.
Neuron Oct, 2009 | Pubmed ID: 19874783
A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2010 | Pubmed ID: 20861372
Circadian rhythms. Temperatures to communicate by.
Science (New York, N.Y.) Oct, 2010 | Pubmed ID: 20947752
Two distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2010 | Pubmed ID: 20980603
NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed.
Cell Apr, 2011 | Pubmed ID: 21514639
A master CLOCK hard at work brings rhythm to the transcriptome.
Genes & development Nov, 2011 | Pubmed ID: 22085960
A morning-induced, phosphorylation-gated repressor times evening gene expression: a new way for circadian clocks to use an old trick.
Molecular cell Dec, 2011 | Pubmed ID: 22152469
A role for O-GlcNAcylation in setting circadian clock speed.
Genes & development Feb, 2012 | Pubmed ID: 22327476
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