Andres J. P. Klein-Szanto

Invasive and metastatic potential of a v-Ha-ras-transformed human bronchial epithelial cell line.

Resistance to serum-induced terminal differentiation in normal human tracheobronchial epithelial cells after in vivo exposure to 7,12-dimethylbenz[a]anthracene.

Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments.

Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.

Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells.

Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4.

Overexpression of cyclin D2 is associated with increased in vivo invasiveness of human squamous carcinoma cells.

Stromelysin-1/matrix metalloproteinase-3 (MMP-3) expression accounts for invasive properties of human astrocytoma cell lines.

Overexpression of the calcium sensor visinin-like protein-1 leads to a cAMP-mediated decrease of in vivo and in vitro growth and invasiveness of squamous cell carcinoma cells.

A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice.

Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status.

Visinin-like protein-1 is a potent inhibitor of cell adhesion and migration in squamous carcinoma cells.

Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.

Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin.

Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts.

PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression.

Proprotein convertases: "master switches" in the regulation of tumor growth and progression.

Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.

Inhibition of proprotein convertases: approaches to block squamous carcinoma development and progression.

IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms.

Increased expression of the pro-protein convertase furin predicts decreased survival in ovarian cancer.

Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication.

TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis.

Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.

VILIP-1 expression in vivo results in decreased mouse skin keratinocyte proliferation and tumor development.

Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasis.

Estrogen and cytochrome P450 1B1 contribute to both early- and late-stage head and neck carcinogenesis.

Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumors.

Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis.

The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation.

Transgenic overexpression of the proprotein convertase furin enhances skin tumor growth.

p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.

Psychosocial functioning and vascular endothelial growth factor in patients with head and neck cancer.

PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers.

Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis.

Biofilm-associated bacterial amyloids dampen inflammation in the gut: oral treatment with curli fibres reduces the severity of hapten-induced colitis in mice.

The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling.

Keep recycling going: New approaches to reduce LDL-C.

Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma.

Correction to: Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.