Scott I. Simon
Department of Biomedical Engineering
University of California, Davis
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Neutrophil tethering on E-selectin activates beta 2 integrin binding to ICAM-1 through a mitogen-activated protein kinase signal transduction pathway.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2000 | Pubmed ID: 10754335
Laboratory investigation; a journal of technical methods and pathology Mar, 2002 | Pubmed ID: 11896209
The Journal of biological chemistry Jun, 2002 | Pubmed ID: 11929876
Leukocyte adhesion dynamics in shear flow.
Annals of biomedical engineering Mar, 2002 | Pubmed ID: 12051617
American journal of physiology. Cell physiology Mar, 2003 | Pubmed ID: 12431911
Hydrodynamic shear and tethering through E-selectin signals phosphorylation of p38 MAP kinase and adhesion of human neutrophils.
Annals of biomedical engineering Sep, 2002 | Pubmed ID: 12449760
Blood Apr, 2003 | Pubmed ID: 12480703
Inflammatory potential of neutrophils detected in sickle cell disease.
American journal of hematology Jun, 2004 | Pubmed ID: 15164377
Shear-dependent capping of L-selectin and P-selectin glycoprotein ligand 1 by E-selectin signals activation of high-avidity beta2-integrin on neutrophils.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2004 | Pubmed ID: 15187162
Annals of biomedical engineering Sep, 2004 | Pubmed ID: 15493506
American journal of physiology. Cell physiology Aug, 2005 | Pubmed ID: 15788481
Mathematical biosciences Mar, 2005 | Pubmed ID: 15836865
The Journal of biological chemistry Aug, 2005 | Pubmed ID: 15955822
Molecular mechanics and dynamics of leukocyte recruitment during inflammation.
Annual review of biomedical engineering , 2005 | Pubmed ID: 16004569
Blood Mar, 2006 | Pubmed ID: 16269618
Ultrasound radiation force enables targeted deposition of model drug carriers loaded on microbubbles.
Journal of controlled release : official journal of the Controlled Release Society Mar, 2006 | Pubmed ID: 16380187
CRP promotes monocyte-endothelial cell adhesion via Fcgamma receptors in human aortic endothelial cells under static and shear flow conditions.
American journal of physiology. Heart and circulatory physiology Sep, 2006 | Pubmed ID: 16603696
Immunity Aug, 2006 | Pubmed ID: 16901726
Molecular imaging Jul, 2006 | Pubmed ID: 16954028
Circulation research Feb, 2007 | Pubmed ID: 17234968
Dynamics of neutrophil membrane compliance and microstructure probed with a micropipet-based piconewton force transducer.
Annals of biomedical engineering Apr, 2007 | Pubmed ID: 17370125
Mechanisms of B-cell synapse formation predicted by Monte Carlo simulation.
Biophysical journal Jun, 2007 | Pubmed ID: 17384077
Journal of leukocyte biology Jun, 2007 | Pubmed ID: 17389580
Vascular mimetics based on microfluidics for imaging the leukocyte--endothelial inflammatory response.
Lab on a chip Apr, 2007 | Pubmed ID: 17389960
Journal of cellular physiology Feb, 2008 | Pubmed ID: 17676580
Journal of leukocyte biology Jan, 2008 | Pubmed ID: 17928459
Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging.
The Journal of investigative dermatology Jul, 2008 | Pubmed ID: 18185533
SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1.
European journal of immunology Feb, 2008 | Pubmed ID: 18196517
Annals of biomedical engineering Apr, 2008 | Pubmed ID: 18253835
Annals of biomedical engineering Apr, 2008 | Pubmed ID: 18278555
Annals of biomedical engineering Apr, 2008 | Pubmed ID: 18317931
Methods in molecular biology (Clifton, N.J.) , 2007 | Pubmed ID: 18453113
Microcirculation (New York, N.Y. : 1994) May, 2008 | Pubmed ID: 18464160
Blood Nov, 2008 | Pubmed ID: 18948585
Leucocyte recruitment under fluid shear: mechanical and molecular regulation within the inflammatory synapse.
Clinical and experimental pharmacology & physiology Feb, 2009 | Pubmed ID: 19018799
Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2008 | Pubmed ID: 19050286
Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding.
American journal of physiology. Cell physiology Apr, 2009 | Pubmed ID: 19176758
Functional role of CD11c+ monocytes in atherogenesis associated with hypercholesterolemia.
Circulation May, 2009 | Pubmed ID: 19433759
Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2009 | Pubmed ID: 19454683
Cancer research Dec, 2009 | Pubmed ID: 19934331
Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow.
Blood Jan, 2010 | Pubmed ID: 19965684
A day (or 5) in a neutrophil's life.
Blood Jul, 2010 | Pubmed ID: 20671133
Mightier than the sickle cell.
Blood Sep, 2010 | Pubmed ID: 20829378
A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings.
PloS one , 2010 | Pubmed ID: 20830204
Arteriosclerosis, thrombosis, and vascular biology Jan, 2011 | Pubmed ID: 21030716
American journal of physiology. Heart and circulatory physiology Mar, 2011 | Pubmed ID: 21169396
The Journal of investigative dermatology Apr, 2011 | Pubmed ID: 21191403
Neutrophil survival and c-kit(+)-progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution.
Blood Mar, 2011 | Pubmed ID: 21278352
Functional characterization of embryonic stem cell-derived endothelial cells.
Journal of vascular research , 2011 | Pubmed ID: 21625175
Migrational guidance of neutrophils is mechanotransduced via high-affinity LFA-1 and calcium flux.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2011 | Pubmed ID: 21632714
Biochemical and biophysical research communications Jul, 2011 | Pubmed ID: 21683067
Journal of neurophysiology Jun, 2012 | Pubmed ID: 22402651
Bone marrow research , 2012 | Pubmed ID: 22762001
Chemokines, selectins and intracellular calcium flux: temporal and spatial cues for leukocyte arrest.
Frontiers in immunology , 2012 | Pubmed ID: 22787461
IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal.
Circulation research Sep, 2012 | Pubmed ID: 22874466
Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice.
PLoS pathogens , 2012 | Pubmed ID: 23209417
On-chip phenotypic analysis of inflammatory monocytes in atherogenesis and myocardial infarction.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2013 | Pubmed ID: 23918401
Clocking leukocytes reveal dynamics of integrin braking.
Biophysical journal Sep, 2013 | Pubmed ID: 24010651
Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress.
PloS one , 2013 | Pubmed ID: 24205197
Coronary artery endothelial cells and microparticles increase expression of VCAM-1 in myocardial infarction.
Thrombosis and haemostasis Mar, 2015 | Pubmed ID: 25413339
Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo.
Nature communications Mar, 2015 | Pubmed ID: 25824568
CD11c/CD18 Signals Very Late Antigen-4 Activation To Initiate Foamy Monocyte Recruitment during the Onset of Hypercholesterolemia.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2015 | Pubmed ID: 26519532
Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation.
Nature communications Nov, 2015 | Pubmed ID: 26612263
Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus.
Frontiers in immunology , 2015 | Pubmed ID: 26635795
Multifactorial Experimental Design to Optimize the Anti-Inflammatory and Proangiogenic Potential of Mesenchymal Stem Cell Spheroids.
Stem cells (Dayton, Ohio) 06, 2017 | Pubmed ID: 28276602
α-Toxin Regulates Local Granulocyte Expansion from Hematopoietic Stem and Progenitor Cells in Infected Wounds.
Journal of immunology (Baltimore, Md. : 1950) 09, 2017 | Pubmed ID: 28733486
Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow.
Blood 11, 2017 | Pubmed ID: 28811304
Neutrophils in hot pursuit of MRSA in the lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America 03, 2018 | Pubmed ID: 29476009
Is CCR6 Required for the Development of Psoriasiform Dermatitis in Mice?
The Journal of investigative dermatology Feb, 2019 | Pubmed ID: 30193756
Selectin-Targeting Peptide-Glycosaminoglycan Conjugates Modulate Neutrophil-Endothelial Interactions.
Cellular and molecular bioengineering , 2019 | Pubmed ID: 30740185
A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection
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