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Capítulo 26

The Cytoskeleton II: Microtubules and Intermediate Filaments

Microtúbulos
Microtúbulos
Microtubules are the thickest cytoskeletal filaments with a diameter of 25 nm. In prokaryotic organisms, microtubules are commonly found in locomotory ...
Inestabilidad de los microtúbulos
Inestabilidad de los microtúbulos
Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound ...
Formación de microtúbulos
Formación de microtúbulos
Microtubules are dynamic structures that undergo continuous assembly and disassembly. They originate from specialized multi-protein complexes known as ...
Proteínas asociadas a microtúbulos (MAP)
Proteínas asociadas a microtúbulos (MAP)
Microtubule function and architecture are regulated by an array of specialized proteins called microtubule-associated proteins or MAPs. These proteins are ...
Desestabilización de microtúbulos
Desestabilización de microtúbulos
The destabilization of microtubules can occur during different stages of the microtubule lifecycle, such as nucleation or elongation. It can take place at ...
Proteínas motoras asociadas a microtúbulos
Proteínas motoras asociadas a microtúbulos
Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they ...
El movimiento de orgánulos y vesículas
El movimiento de orgánulos y vesículas
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These ...
Ensamblaje de estructuras complejas de microtúbulos
Ensamblaje de estructuras complejas de microtúbulos
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular ...
Microtúbulos en la motilidad celular
Microtúbulos en la motilidad celular
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form ...
Mecanismo del movimiento ciliar
Mecanismo del movimiento ciliar
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible ...
Microtúbulos en la señalización
Microtúbulos en la señalización
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like ...
Fármacos que estabilizan los microtúbulos
Fármacos que estabilizan los microtúbulos
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the ...
Fármacos que desestabilizan los microtúbulos
Fármacos que desestabilizan los microtúbulos
Microtubules are dynamic structures and can be regulated by microtubule targeting agents (MTAs). Microtubule destabilizing drugs are a class of MTAs that ...
La estructura de los filamentos intermedios
La estructura de los filamentos intermedios
The intermediate filaments are one of three widely studied cytoskeletal filaments. They are so named as their diameter (10 nm) is in between that of ...
Tipos de filamentos intermedios
Tipos de filamentos intermedios
The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and ...
Formación de filamentos intermedios
Formación de filamentos intermedios
Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two ...
Desmontaje de filamentos intermedios
Desmontaje de filamentos intermedios
Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to ...
Septinos
Septinos
Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. ...
Papel de los septinos
Papel de los septinos
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate ...
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