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Kapitel 26

Das Zytoskelett II: Mikrotubuli und Intermediärfilamente

Mikrotubuli
Mikrotubuli
Microtubules are the thickest cytoskeletal filaments with a diameter of 25 nm. In prokaryotic organisms, microtubules are commonly found in locomotory ...
Mikrotubuli-Instabilität
Mikrotubuli-Instabilität
Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound ...
Mikrotubuli-Formation
Mikrotubuli-Formation
Microtubules are dynamic structures that undergo continuous assembly and disassembly. They originate from specialized multi-protein complexes known as ...
Mikrotubuli-assoziierte Proteine (MAPs)
Mikrotubuli-assoziierte Proteine (MAPs)
Microtubule function and architecture are regulated by an array of specialized proteins called microtubule-associated proteins or MAPs. These proteins are ...
Destabilisierung von Mikrotubuli
Destabilisierung von Mikrotubuli
The destabilization of microtubules can occur during different stages of the microtubule lifecycle, such as nucleation or elongation. It can take place at ...
Mikrotubuli-assoziierte Motorproteine
Mikrotubuli-assoziierte Motorproteine
Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they ...
Die Bewegung von Organellen und Vesikeln
Die Bewegung von Organellen und Vesikeln
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These ...
Aufbau komplexer Mikrotubuli-Strukturen
Aufbau komplexer Mikrotubuli-Strukturen
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular ...
Mikrotubuli in der Zellmotilität
Mikrotubuli in der Zellmotilität
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form ...
Mechanismus der Ziliarbewegung
Mechanismus der Ziliarbewegung
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible ...
Mikrotubuli in der Signalübertragung
Mikrotubuli in der Signalübertragung
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like ...
Medikamente, die Mikrotubuli stabilisieren
Medikamente, die Mikrotubuli stabilisieren
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the ...
Medikamente, die Mikrotubuli destabilisieren
Medikamente, die Mikrotubuli destabilisieren
Microtubules are dynamic structures and can be regulated by microtubule targeting agents (MTAs). Microtubule destabilizing drugs are a class of MTAs that ...
Die Struktur der Intermediärfilamente
Die Struktur der Intermediärfilamente
The intermediate filaments are one of three widely studied cytoskeletal filaments. They are so named as their diameter (10 nm) is in between that of ...
Arten von Intermediärfilamenten
Arten von Intermediärfilamenten
The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and ...
Bildung von Intermediärfilamenten
Bildung von Intermediärfilamenten
Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two ...
Abbau von Intermediärfilamenten
Abbau von Intermediärfilamenten
Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to ...
Septine
Septine
Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. ...
Rolle der Septine
Rolle der Septine
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate ...
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