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Bölüm 26

Sitoskeleton II: Mikrotübüller ve Ara Filamentler

Mikrotübüller
Mikrotübüller
Microtubules are the thickest cytoskeletal filaments with a diameter of 25 nm. In prokaryotic organisms, microtubules are commonly found in locomotory ...
Mikrotübül İnstabilitesi
Mikrotübül İnstabilitesi
Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound ...
Mikrotübül Oluşumu
Mikrotübül Oluşumu
Microtubules are dynamic structures that undergo continuous assembly and disassembly. They originate from specialized multi-protein complexes known as ...
Mikrotübül İlişkili Proteinler (MAP'ler)
Mikrotübül İlişkili Proteinler (MAP'ler)
Microtubule function and architecture are regulated by an array of specialized proteins called microtubule-associated proteins or MAPs. These proteins are ...
Mikrotübüllerin Destabilizasyonu
Mikrotübüllerin Destabilizasyonu
The destabilization of microtubules can occur during different stages of the microtubule lifecycle, such as nucleation or elongation. It can take place at ...
Mikrotübül İlişkili Motor Proteinler
Mikrotübül İlişkili Motor Proteinler
Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they ...
Organellerin ve Veziküllerin Hareketi
Organellerin ve Veziküllerin Hareketi
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These ...
Karmaşık mikrotübül yapılarının montajı
Karmaşık mikrotübül yapılarının montajı
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular ...
Hücre motilitesindeki mikrotübüller
Hücre motilitesindeki mikrotübüller
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form ...
siliyer hareket mekanizması
siliyer hareket mekanizması
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible ...
Sinyalizasyonda Mikrotübüller
Sinyalizasyonda Mikrotübüller
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like ...
Mikrotübülleri Stabilize Eden İlaçlar
Mikrotübülleri Stabilize Eden İlaçlar
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the ...
Mikrotübülleri Destabilize Eden İlaçlar
Mikrotübülleri Destabilize Eden İlaçlar
Microtubules are dynamic structures and can be regulated by microtubule targeting agents (MTAs). Microtubule destabilizing drugs are a class of MTAs that ...
Ara Filamentlerin Yapısı
Ara Filamentlerin Yapısı
The intermediate filaments are one of three widely studied cytoskeletal filaments. They are so named as their diameter (10 nm) is in between that of ...
Ara Filament Çeşitleri
Ara Filament Çeşitleri
The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and ...
Ara Filamentlerin Oluşumu
Ara Filamentlerin Oluşumu
Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two ...
Ara filamentlerin sökülmesi
Ara filamentlerin sökülmesi
Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to ...
Septinler
Septinler
Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. ...
Septinlerin Rolü
Septinlerin Rolü
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate ...
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