Results: Morphology and Immunofluorescence in Control and Cilia Mutant Cochlea
6:16
Conclusion
Transcribir
The overall goal of this protocol is to examine ciliary mutant mouse cochlea for planar-cell-polarity phenotypes. These techniques allow for an extensive detailing of the cochlear phenotype, which will lead to a more precise understanding of the c
Inicia sesión o comienza tu prueba gratuita para acceder a este contenido
Primary cilia influence various signaling pathways. The mammalian cochlea is ideal for examining planar cell polarity (PCP) signaling. Cilia dysfunction affects cochlear outgrowth, cellular patterning and hair cell orientation, readouts of PCP. Our goal is to analyze PCP signaling in mouse cochlea via phenotypic analysis, immunohistochemistry and scanning electron microscopy.