Preparation of Silk Nanoparticles from Bombyx mori Cocoons
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Preparation of Doxorubicin-loaded Silk Nanoparticles
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In Vitro Cytotoxicity of Control and Doxorubicin-loaded Silk Nanoparticles
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Results: Characterization and In Vitro Cytotoxicity of Silk Nanoparticles and Doxorubicin-loaded Silk Nanoparticles
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Conclusion
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The overall goal of this procedure is to manufacture silk nanoparticles from a reverse-engineered aqueous silk solution, and subsequently use these silk nanoparticles for drug-delivery applications. So this method utilized nano-precipitation to ge
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Nanoparticles are emerging as promising drug delivery systems for a broad range of indications. Here, we describe a simple yet powerful method to manufacture silk nanoparticles using reverse engineered Bombyx mori silk. These silk nanoparticles can be readily loaded with a therapeutic payload and subsequently explored for drug delivery applications.