Results: Transgene Expression in Retinal Progenitors from Donor Cells
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Conclusion
Transcripción
The overall goal of these procedures is to study how changes in gene expression, either within developing cells or in their surrounding environment, influence temporal processes during development. This method can help answer key questions, such a
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Live tracking of individual WT retinal progenitors in distinct genetic backgrounds allows for the assessment of the contribution of cell non-autonomous signaling during neurogenesis. Here, a combination of gene knockdown, chimera generation via embryo transplantation and in vivo time-lapse confocal imaging was utilized for this purpose.