Tissue-Specific and Inducible Braf/Pten Metastatic Melanoma Mouse Model
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Conclusion
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Our method enables monitoring the increase in metastatic involvement of inguinal lymph nodes by measuring the increase in their volume. This uninvasive method is very well-tolerated, therefore, multiple imaging sessions can be scheduled on the sam
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Melanoma is a very aggressive disease that quickly spreads to other organs. This protocol describes the application of ultra-high-frequency ultrasound imaging, coupled with 3D rendering, to monitor the volume of the inguinal lymph nodes in the Braf/Pten mouse model of metastatic melanoma.