Results: Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model
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conclusion
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By using a direct intra-aortal cell-tracer application, we can analyze the role of endothelial cells originating from the parent artery in neointima formation at two different time points. A big advantage of this technique is a direct, one-point,
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We performed a one-point, lipophilic cell-tracer injection to track endothelial cells, followed by an arteriotomy and suturing of sidewall aneurysms on the abdominal rat aorta. Neointima formation seemed dependent on the parent artery in decellularized aneurysms and was promoted by the recruitment from aneurysm wall cells in vital cell-rich walls.