Laboratory of Molecular Medicine and Neuroscience
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HIV-1 and the brain: connections between HIV-1-associated dementia, neuropathology and neuroimmunology.
Microbes and infection / Institut Pasteur Mar, 2002 | Pubmed ID: 11909740
Analysis of the temporal expression of nestin in human fetal brain derived neuronal and glial progenitor cells.
Brain research. Developmental brain research Mar, 2002 | Pubmed ID: 11947939
Traffic of JC virus from sites of initial infection to the brain: the path to progressive multifocal leukoencephalopathy.
The Journal of infectious diseases Dec, 2002 | Pubmed ID: 12424695
Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport.
The Journal of biological chemistry Apr, 2003 | Pubmed ID: 12551932
Serological cross-reactivities between antibodies to simian virus 40, BK virus, and JC virus assessed by virus-like-particle-based enzyme immunoassays.
Clinical and diagnostic laboratory immunology Mar, 2003 | Pubmed ID: 12626455
Advances in the biology of JC virus and induction of progressive multifocal leukoencephalopathy.
Journal of neurovirology Apr, 2003 | Pubmed ID: 12707854
Basic, clinical, and epidemiological studies of progressive multifocal leukoencephalopathy: implications for therapy.
Journal of neurovirology , 2003 | Pubmed ID: 12709863
Lineage pathway of human brain progenitor cells identified by JC virus susceptibility.
Annals of neurology May, 2003 | Pubmed ID: 12730998
Serum antibodies to JC virus, BK virus, simian virus 40, and the risk of incident adult astrocytic brain tumors.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology May, 2003 | Pubmed ID: 12750243
Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2003 | Pubmed ID: 12843275
Analysis of the excreted JC virus strains and their potential oral transmission.
Journal of neurovirology Aug, 2003 | Pubmed ID: 12907394
HIV-2 derived lentiviral vectors: gene transfer in Parkinson's and Fabry disease models in vitro.
Journal of medical virology Oct, 2003 | Pubmed ID: 12938190
JC virus induces nonapoptotic cell death of human central nervous system progenitor cell-derived astrocytes.
Journal of virology May, 2004 | Pubmed ID: 15078969
Human immunodeficiency virus type 1 infection of human brain-derived progenitor cells.
Journal of virology Jul, 2004 | Pubmed ID: 15220405
Comparison of PCR-southern hybridization and quantitative real-time PCR for the detection of JC and BK viral nucleotide sequences in urine and cerebrospinal fluid.
Journal of virological methods Nov, 2004 | Pubmed ID: 15381359
Differential effects of interferon-gamma on the expression of cyclooxygenase-2 in high-grade human gliomas versus primary astrocytes.
Journal of neuroimmunology Nov, 2004 | Pubmed ID: 15465602
Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories.
International journal of cancer. Journal international du cancer Feb, 2005 | Pubmed ID: 15499616
Nuclear receptor activation and interaction with morphine.
Journal of neuroimmunology Dec, 2004 | Pubmed ID: 15579281
Herpes simplex virus type 1 enters human epidermal keratinocytes, but not neurons, via a pH-dependent endocytic pathway.
Journal of virology Jun, 2005 | Pubmed ID: 15919913
Variant-specific tropism of human herpesvirus 6 in human astrocytes.
Journal of virology Aug, 2005 | Pubmed ID: 16014907
Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremia.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Sep, 2005 | Pubmed ID: 16095500
Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells.
Glia Jan, 2006 | Pubmed ID: 16206198
Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy.
The New England journal of medicine Mar, 2006 | Pubmed ID: 16510746
JC virus can infect human immune and nervous system progenitor cells: implications for pathogenesis.
Advances in experimental medicine and biology , 2006 | Pubmed ID: 16626042
Neural progenitors and HIV-1-associated central nervous system disease in adults and children.
Current HIV research Jul, 2006 | Pubmed ID: 16842084
Interactions between c-Jun, nuclear factor 1, and JC virus promoter sequences: implications for viral tropism.
Journal of virology Nov, 2006 | Pubmed ID: 16928756
Viral proteomics: a promising approach for understanding JC virus tropism.
Proteomics Oct, 2006 | Pubmed ID: 16991198
Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A in astrocytes and in T-cells.
Journal of medical virology Dec, 2006 | Pubmed ID: 17063514
Induction of original phenotype of human immortalized chondrocytes: a quantitative gene expression analysis.
International journal of molecular medicine Jan, 2007 | Pubmed ID: 17143552
MEK1/2 inhibitors block basal and transforming growth factor 1beta1-stimulated JC virus multiplication.
Journal of virology Jun, 2007 | Pubmed ID: 17409139
Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring.
Lancet neurology May, 2007 | Pubmed ID: 17434098
Evidence of human immunodeficiency virus type 1 infection of nestin-positive neural progenitors in archival pediatric brain tissue.
Journal of neurovirology Jun, 2007 | Pubmed ID: 17613718
NeuroAIDS, drug abuse, and inflammation: building collaborative research activities.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Dec, 2006 | Pubmed ID: 18040811
DNA-binding transcription factor NF-1A negatively regulates JC virus multiplication.
The Journal of general virology Jun, 2008 | Pubmed ID: 18474555
BK virus antibody titers and intensity of infections after renal transplantation.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Oct, 2008 | Pubmed ID: 18676176
Neuropharmacology of HIV/AIDS.
Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn , 2007 | Pubmed ID: 18808990
M- and T-tropic HIVs promote apoptosis in rat neurons.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Mar, 2009 | Pubmed ID: 19034668
Glial cell type-specific subcellular localization of 14-3-3 zeta: an implication for JCV tropism.
Glia Jul, 2009 | Pubmed ID: 19062179
Response to Linberg et al. Natalizumab alters transcriptional expression profiles of blood cell subpopulations of multiple sclerosis patients.
Journal of neuroimmunology Nov, 2008 | Pubmed ID: 19117088
Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project.
Blood May, 2009 | Pubmed ID: 19264918
Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project.
The lancet oncology Aug, 2009 | Pubmed ID: 19647202
Progressive multifocal leukoencephalopathy in patients on immunomodulatory therapies.
Annual review of medicine , 2010 | Pubmed ID: 19719397
Reemergence of PML in natalizumab-treated patients--new cases, same concerns.
The New England journal of medicine Sep, 2009 | Pubmed ID: 19741226
Progressive multifocal leukoencephalopathy after natalizumab monotherapy.
The New England journal of medicine Sep, 2009 | Pubmed ID: 19741229
Monoclonal antibodies and progressive multifocal leukoencephalopathy.
mAbs Nov-Dec, 2009 | Pubmed ID: 20073129
Molecular regulation of JC virus tropism: insights into potential therapeutic targets for progressive multifocal leukoencephalopathy.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Sep, 2010 | Pubmed ID: 20401541
Rearranged JC virus noncoding control regions found in progressive multifocal leukoencephalopathy patient samples increase virus early gene expression and replication rate.
Journal of virology Oct, 2010 | Pubmed ID: 20686041
JC virus persistence following progressive multifocal leukoencephalopathy in multiple sclerosis patients treated with natalizumab.
Annals of neurology Sep, 2010 | Pubmed ID: 20818792
Hexadecyloxypropyl-cidofovir (CMX001) suppresses JC virus replication in human fetal brain SVG cell cultures.
Antimicrobial agents and chemotherapy Nov, 2010 | Pubmed ID: 20823288
Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity.
The Journal of general virology Dec, 2010 | Pubmed ID: 20826618
CMX001 (1-O-hexadecyloxypropyl-cidofovir) inhibits polyomavirus JC replication in human brain progenitor-derived astrocytes.
Antimicrobial agents and chemotherapy May, 2011 | Pubmed ID: 21402853
Inhibitory interactions between BK and JC virus among kidney transplant recipients.
Journal of the American Society of Nephrology : JASN May, 2011 | Pubmed ID: 21511831
IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2011 | Pubmed ID: 21562161
Taxonomical developments in the family Polyomaviridae.
Archives of virology Sep, 2011 | Pubmed ID: 21562881
Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring.
Lancet neurology Aug, 2011 | Pubmed ID: 21777829
JC virus promoter/enhancers contain TATA box-associated Spi-B-binding sites that support early viral gene expression in primary astrocytes.
The Journal of general virology Mar, 2012 | Pubmed ID: 22071512
History and current concepts in the pathogenesis of PML.
Cleveland Clinic journal of medicine Nov, 2011 | Pubmed ID: 22123932
The link between VLA-4 and JC virus reactivation.
Expert review of clinical immunology Jan, 2012 | Pubmed ID: 22149341
Individuals infected with JC polyomavirus do not present detectable JC virus DNA in oropharyngeal fluids.
The Journal of general virology Apr, 2012 | Pubmed ID: 22158878
Neurological infections: risks of globalisation and new drugs.
Lancet neurology Jan, 2012 | Pubmed ID: 22172615
Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain.
Clinical microbiology reviews Jul, 2012 | Pubmed ID: 22763635
Changes in JC Virus-Specific T Cell Responses during Natalizumab Treatment and in Natalizumab-Associated Progressive Multifocal Leukoencephalopathy.
PLoS pathogens Nov, 2012 | Pubmed ID: 23144619
Human Immunodeficiency Virus Type 1 (HIV-1) Transactivator of Transcription through Its Intact Core and Cysteine-Rich Domains Inhibits Wnt/β-Catenin Signaling in Astrocytes: Relevance to HIV Neuropathogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2012 | Pubmed ID: 23152614