Department of Neuroscience
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Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease.
Nature medicine Jun, 2002 | Pubmed ID: 12042811
Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.
Molecular and cellular biology Jan, 2004 | Pubmed ID: 14701757
Degradation of BACE by the ubiquitin-proteasome pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2004 | Pubmed ID: 15289451
Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region.
Journal of neurochemistry Sep, 2004 | Pubmed ID: 15341527
BACE1 gene expression and protein degradation.
Annals of the New York Academy of Sciences Dec, 2004 | Pubmed ID: 15681800
Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2005 | Pubmed ID: 15857888
Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2006 | Pubmed ID: 16449801
Leaky scanning and reinitiation regulate BACE1 gene expression.
Molecular and cellular biology May, 2006 | Pubmed ID: 16611980
Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2006 | Pubmed ID: 16816111
BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2006 | Pubmed ID: 16816112
Ubiquitin-proteasome pathway mediates degradation of APH-1.
Journal of neurochemistry Dec, 2006 | Pubmed ID: 17059559
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2006 | Pubmed ID: 17121991
Recent advances in basic neurosciences and brain disease: from synapses to behavior.
Molecular pain , 2006 | Pubmed ID: 17196111
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.
Journal of lipid research May, 2007 | Pubmed ID: 17293612
Degradation of nicastrin involves both proteasome and lysosome.
Journal of neurochemistry May, 2007 | Pubmed ID: 17326768
SP1 regulates a human SNAP-25 gene expression.
Journal of neurochemistry Apr, 2008 | Pubmed ID: 18194215
Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
Neurobiology of aging Jun, 2010 | Pubmed ID: 18687504
Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models.
The Journal of experimental medicine Nov, 2008 | Pubmed ID: 18955571
TMP21 degradation is mediated by the ubiquitin-proteasome pathway.
The European journal of neuroscience Nov, 2008 | Pubmed ID: 19046380
Preparation of PbS Nanoparticles by Phase-Transfer Method and Application to Pb-Selective Electrode Based on PVC Membrane.
Analytical letters Oct, 2008 | Pubmed ID: 19112518
Upregulation of macrophage migration inhibitory factor gene expression in stroke.
Stroke; a journal of cerebral circulation Mar, 2009 | Pubmed ID: 19131653
Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2009 | Pubmed ID: 19509306
BACE1 gene promoter single-nucleotide polymorphisms in Alzheimer's disease.
Journal of molecular neuroscience : MN Sep, 2010 | Pubmed ID: 20455082
NF-κB signaling inhibits ubiquitin carboxyl-terminal hydrolase L1 gene expression.
Journal of neurochemistry Mar, 2011 | Pubmed ID: 21210816
Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation.
The Journal of biological chemistry Mar, 2011 | Pubmed ID: 21216952
Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) Feb, 2011 | Pubmed ID: 21329555
Transcriptional Regulation of TMP21 by NFAT.
Molecular neurodegeneration , 2011 | Pubmed ID: 21375783
Loss of activated CaMKII at the synapse underlies Alzheimer's disease memory loss.
Journal of neurochemistry Nov, 2011 | Pubmed ID: 21899538
Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer's disease.
Journal of neurochemistry Jan, 2012 | Pubmed ID: 22122349
Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.
Journal of neurochemistry Dec, 2011 | Pubmed ID: 22212137
低氧调节的 ATP13A2 (PARK9) 基因转录。
Journal of neurochemistry Jan, 2012 | Pubmed ID: 22288903