Shinya Yamamoto

Sequoia regulates cell fate decisions in the external sensory organs of adult Drosophila.

Endocytosis and intracellular trafficking of Notch and its ligands.

dEHBP1 controls exocytosis and recycling of Delta during asymmetric divisions.

A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands.

Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells.

The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit.

Drosophila EHBP1 regulates Scabrous secretion during Notch-mediated lateral inhibition.

Protein phosphatase 1ß limits ring canal constriction during Drosophila germline cyst formation.

Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.

Shared mechanisms between Drosophila peripheral nervous system development and human neurodegenerative diseases.

Dopamine dynamics and signaling in Drosophila: an overview of genes, drugs and behavioral paradigms.

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.

Introduction to Notch signaling.

Large-scale identification of chemically induced mutations in Drosophila melanogaster.

A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases.

Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production.

Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration.

Fruit flies in biomedical research.

A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis.

Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress.

Morgan's legacy: fruit flies and the functional annotation of conserved genes.

WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes.

Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.

Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration.

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.

A Syndromic Neurodevelopmental Disorder Caused by De Novo Variants in EBF3.

Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration.

MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.

Neutral Competition for Drosophila Follicle and Cyst Stem Cell Niches Requires Vesicle Trafficking Genes.

Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially.

Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research.

Pleiotropic neuropathological and biochemical alterations associated with Myo5a mutation in a rat Model.

Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder.

A gene-specific library for .

Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder.

Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases.

IRF2BPL Is Associated with Neurological Phenotypes.

Rapid and Integrative Discovery of Retina Regulatory Molecules.

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease.

Unraveling Novel Mechanisms of Neurodegeneration Through a Large-Scale Forward Genetic Screen in .

Unweaving the role of nuclear Lamins in neural circuit integrity.

The fruit fly at the interface of diagnosis and pathogenic mechanisms of rare and common human diseases.

De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia.