Department of Biochemistry
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Advanced glycation end products (AGE) inhibit scavenger receptor class B type I-mediated reverse cholesterol transport: a new crossroad of AGE to cholesterol metabolism.
Journal of atherosclerosis and thrombosis , 2003 | Pubmed ID: 12621157
Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis.
Current opinion in investigational drugs (London, England : 2000) Sep, 2003 | Pubmed ID: 14582454
Genomic organization, expression, and comparative analysis of noncoding region of the rat Ndrg4 gene.
Gene Jan, 2004 | Pubmed ID: 14693380
[Acyl-coenzyme A: cholesterol acyltransferase (ACAT)].
Nihon rinsho. Japanese journal of clinical medicine Dec, 2004 | Pubmed ID: 15658270
High prevalence of Chlamydia pneumoniae antibodies and increased high-sensitive C-reactive protein in patients with vascular dementia.
Journal of the American Geriatrics Society Apr, 2005 | Pubmed ID: 15817002
Serotonin acts as an up-regulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages.
Atherosclerosis Jun, 2006 | Pubmed ID: 16157345
Human urotensin II accelerates foam cell formation in human monocyte-derived macrophages.
Hypertension (Dallas, Tex. : 1979) Oct, 2005 | Pubmed ID: 16172428
Relationship between serum insulin-like growth factor-1 levels and Alzheimer's disease and vascular dementia.
Journal of the American Geriatrics Society Oct, 2005 | Pubmed ID: 16181175
Ndrg4 enhances NGF-induced ERK activation uncoupled with Elk-1 activation.
Journal of cellular biochemistry May, 2006 | Pubmed ID: 16408304
Inhibitors of acyl-coenzyme a: cholesterol acyltransferase.
Current drug targets. Cardiovascular & haematological disorders Dec, 2005 | Pubmed ID: 16503866
Human urotensin II as a link between hypertension and coronary artery disease.
Hypertension research : official journal of the Japanese Society of Hypertension Jun, 2006 | Pubmed ID: 16940699
Impact of increased plasma serotonin levels and carotid atherosclerosis on vascular dementia.
Atherosclerosis Nov, 2007 | Pubmed ID: 17049533
Increased human urotensin II levels are correlated with carotid atherosclerosis in essential hypertension.
American journal of hypertension Feb, 2007 | Pubmed ID: 17261470
Human urotensin-II potentiates the mitogenic effect of mildly oxidized low-density lipoprotein on vascular smooth muscle cells: comparison with other vasoactive agents and hydrogen peroxide.
Hypertension research : official journal of the Japanese Society of Hypertension Oct, 2006 | Pubmed ID: 17283870
Use of serum insulin-like growth factor-I levels to predict psychiatric non-response to donepezil in patients with Alzheimer's disease.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society Feb, 2008 | Pubmed ID: 17714966
Impact of salusin-alpha and -beta on human macrophage foam cell formation and coronary atherosclerosis.
Circulation Feb, 2008 | Pubmed ID: 18212280
Increased plasma urotensin-II levels are associated with diabetic retinopathy and carotid atherosclerosis in Type 2 diabetes.
Clinical science (London, England : 1979) Dec, 2008 | Pubmed ID: 18338983
Serum salusin-alpha levels are decreased and correlated negatively with carotid atherosclerosis in essential hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension Mar, 2008 | Pubmed ID: 18497465
Chronic urotensin II infusion enhances macrophage foam cell formation and atherosclerosis in apolipoprotein E-knockout mice.
Journal of hypertension Oct, 2008 | Pubmed ID: 18806619
Angiotensin II upregulates acyl-CoA:cholesterol acyltransferase-1 via the angiotensin II Type 1 receptor in human monocyte-macrophages.
Hypertension research : official journal of the Japanese Society of Hypertension Sep, 2008 | Pubmed ID: 18971559
Human urotensin II promotes hypertension and atherosclerotic cardiovascular diseases.
Current medicinal chemistry , 2009 | Pubmed ID: 19199921
Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages.
American journal of physiology. Endocrinology and metabolism Aug, 2009 | Pubmed ID: 19625677
Increased plasma urotensin-II and carotid atherosclerosis are associated with vascular dementia.
Journal of atherosclerosis and thrombosis Jun, 2009 | Pubmed ID: 19638714
Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis.
Circulation research Aug, 2009 | Pubmed ID: 19644050
Chronic infusion of salusin-alpha and -beta exerts opposite effects on atherosclerotic lesion development in apolipoprotein E-deficient mice.
Atherosclerosis Sep, 2010 | Pubmed ID: 20684826
Purification of recombinant acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) from H293 cells and binding studies between the enzyme and substrates using difference intrinsic fluorescence spectroscopy.
Biochemistry Nov, 2010 | Pubmed ID: 20964445
m-Calpain induction in vascular endothelial cells on human and mouse atheromas and its roles in VE-cadherin disorganization and atherosclerosis.
Circulation Dec, 2011 | Pubmed ID: 22064597
Effects of PKF275-055, a dipeptidyl peptidase-4 inhibitor, on the development of atherosclerotic lesions in apolipoprotein E-null mice.
Metabolism: clinical and experimental Jul, 2012 | Pubmed ID: 22225957
Hydrogen peroxide-inducible clone 5 (Hic-5) as a potential therapeutic target for vascular and other disorders.
Journal of atherosclerosis and thrombosis , 2012 | Pubmed ID: 22472216
Coexpression of CCR6 and CD146 (MCAM) is a marker of effector memory T-helper 17 cells.
The Journal of dermatology Oct, 2012 | Pubmed ID: 22486269
Salusin-β accelerates inflammatory responses in vascular endothelial cells via NF-κB signaling in LDL receptor-deficient mice in vivo and HUVECs in vitro.
American journal of physiology. Heart and circulatory physiology Jul, 2012 | Pubmed ID: 22561298
Calpain and atherosclerosis.
Journal of atherosclerosis and thrombosis , 2013 | Pubmed ID: 23171729
Time course-changes in phosphatidylcholine profile during oxidative modification of low-density lipoprotein.
Lipids in health and disease Mar, 2014 | Pubmed ID: 24625108
Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms.
Journal of the American Heart Association May, 2014 | Pubmed ID: 24811612
NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2014 | Pubmed ID: 25189573
Role of Hic-5 in the formation of microvilli-like structures and the monocyte-endothelial interaction that accelerates atherosclerosis.
Cardiovascular research Mar, 2015 | Pubmed ID: 25587044
Calpastatin counteracts pathological angiogenesis by inhibiting suppressor of cytokine signaling 3 degradation in vascular endothelial cells.
Circulation research Mar, 2015 | Pubmed ID: 25648699
Hydrogen peroxide-inducible clone-5 regulates mesangial cell proliferation in proliferative glomerulonephritis in mice.
PloS one , 2015 | Pubmed ID: 25835392
Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice.
Journal of hepatology Jan, 2016 | Pubmed ID: 26334580
Fibroblast growth factor-23 induces cellular senescence in human mesenchymal stem cells from skeletal muscle.
Biochemical and biophysical research communications Feb, 2016 | Pubmed ID: 26797283
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke.
Journal of molecular neuroscience : MN Jun, 2016 | Pubmed ID: 26910758
Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases.
Journal of atherosclerosis and thrombosis Jan, 2017 | Pubmed ID: 27476665
Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.
The Journal of clinical investigation 09, 2016 | Pubmed ID: 27525442
Potential contribution of the hepcidin-macrophage axis to plaque vulnerability in acute myocardial infarction in human.
International journal of cardiology Jan, 2017 | Pubmed ID: 27855289
Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells.
Scientific reports 02, 2017 | Pubmed ID: 28150810
Emerging roles of calpain proteolytic systems in macrophage cholesterol handling.
Cellular and molecular life sciences : CMLS 08, 2017 | Pubmed ID: 28432377
Dysregulation of Calpain Proteolytic Systems Underlies Degenerative Vascular Disorders.
Journal of atherosclerosis and thrombosis Jan, 2018 | Pubmed ID: 28819082
The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
Oncogene 03, 2018 | Pubmed ID: 29242607
Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.
Scientific reports 02, 2018 | Pubmed ID: 29391479
Impact of Dysfunctional Protein Catabolism on Macrophage Cholesterol Handling.
Current medicinal chemistry , 2019 | Pubmed ID: 29589525
Endothelial calpain systems orchestrate myofibroblast differentiation during wound healing.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2019 | Pubmed ID: 30199285
Thrombolytic Therapy for Acute Ischemic Stroke: Past and Future.
Current pharmaceutical design , 2019 | Pubmed ID: 30892155
Priming with erythropoietin enhances cell survival and angiogenic effect of mesenchymal stem cell implantation in rat limb ischemia.
Regenerative therapy Jun, 2016 | Pubmed ID: 31245482