Cell,
Developmental and Integrative Biology Department,
Cell, Developmental and Integrative Biology Department
Rosa Serra has not added Biography.
If you are Rosa Serra and would like to personalize this page please email our Author Liaison for assistance.
Unique and redundant roles of Smad3 in TGF-beta-mediated regulation of long bone development in organ culture.
Developmental dynamics : an official publication of the American Association of Anatomists Aug, 2004 | Pubmed ID: 15254903
Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones.
Developmental biology Dec, 2004 | Pubmed ID: 15531369
TGF-beta in mammary gland development and breast cancer.
Breast disease , 2003 | Pubmed ID: 15687689
TGF-beta, c-Cbl, and PDGFR-alpha the in mammary stroma.
Developmental biology Mar, 2005 | Pubmed ID: 15708558
Mouse models of transforming growth factor beta impact in breast development and cancer.
Endocrine-related cancer Dec, 2005 | Pubmed ID: 16322320
Transforming growth factor-beta signaling helps specify tumor type in DMBA and hormone-induced mammary cancers.
Differentiation; research in biological diversity Feb, 2006 | Pubmed ID: 16466399
Tgfbr2 regulates the maintenance of boundaries in the axial skeleton.
Developmental biology Aug, 2006 | Pubmed ID: 16824508
Intraflagellar transport is essential for endochondral bone formation.
Development (Cambridge, England) Jan, 2007 | Pubmed ID: 17166921
Development of the post-natal growth plate requires intraflagellar transport proteins.
Developmental biology May, 2007 | Pubmed ID: 17359961
Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis.
Development (Cambridge, England) Jun, 2007 | Pubmed ID: 17507416
Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints.
Developmental biology Oct, 2007 | Pubmed ID: 17822689
Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth.
Development (Cambridge, England) Nov, 2007 | Pubmed ID: 17898001
Intraflagellar transport in skeletal development.
Journal of musculoskeletal & neuronal interactions Oct-Dec, 2007 | Pubmed ID: 18094483
Transforming growth factor-beta signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung.
American journal of physiology. Lung cellular and molecular physiology Jul, 2008 | Pubmed ID: 18487357
Role for primary cilia in the regulation of mouse ovarian function.
Developmental dynamics : an official publication of the American Association of Anatomists Aug, 2008 | Pubmed ID: 18629867
Role of intraflagellar transport and primary cilia in skeletal development.
Anatomical record (Hoboken, N.J. : 2007) Sep, 2008 | Pubmed ID: 18727103
Cilia involvement in patterning and maintenance of the skeleton.
Current topics in developmental biology , 2008 | Pubmed ID: 19147010
Loss of TGF-beta or Wnt5a results in an increase in Wnt/beta-catenin activity and redirects mammary tumour phenotype.
Breast cancer research : BCR , 2009 | Pubmed ID: 19344510
TGF-beta promotes Th17 cell development through inhibition of SOCS3.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2009 | Pubmed ID: 19535626
Tgfbr2 is required for development of the skull vault.
Developmental biology Oct, 2009 | Pubmed ID: 19699732
PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development.
The EMBO journal Mar, 2010 | Pubmed ID: 20075866
Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.
BMC developmental biology Mar, 2010 | Pubmed ID: 20214815
Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Oct, 2010 | Pubmed ID: 20530462
Inhibiting breast cancer progression by exploiting TGFbeta signaling.
Current drug targets Sep, 2010 | Pubmed ID: 20545612
TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine.
Gastroenterology Jan, 2011 | Pubmed ID: 20875417
Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B.
Human molecular genetics Jan, 2011 | Pubmed ID: 20962035
Wnt5a as an effector of TGFβ in mammary development and cancer.
Journal of mammary gland biology and neoplasia Jun, 2011 | Pubmed ID: 21416313
Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development.
Cells, tissues, organs , 2011 | Pubmed ID: 21597273
Misexpression of wingless-related MMTV integration site 5A in mouse mammary gland inhibits the milk ejection response and regulates connexin43 phosphorylation.
Biology of reproduction Nov, 2011 | Pubmed ID: 21753195
Depletion of primary cilia in articular chondrocytes results in reduced Gli3 repressor to activator ratio, increased Hedgehog signaling, and symptoms of early osteoarthritis.
Osteoarthritis and cartilage Feb, 2012 | Pubmed ID: 22173325
PDGF mediates TGFβ-induced migration during development of the spinous process.
Developmental biology May, 2012 | Pubmed ID: 22369999
Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage.
Arthritis research & therapy Mar, 2012 | Pubmed ID: 22394585
Ift88 regulates Hedgehog signaling, Sfrp5 expression, and β-catenin activity in post-natal growth plate.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Mar, 2013 | Pubmed ID: 23034798
WNT5A inhibits metastasis and alters splicing of Cd44 in breast cancer cells.
PloS one , 2013 | Pubmed ID: 23484019
Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation.
Developmental biology Oct, 2013 | Pubmed ID: 23933490
Normal mammary development and function in mice with Ift88 deleted in MMTV- and K14-Cre expressing cells.
Cilia Mar, 2014 | Pubmed ID: 24594320
Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Dec, 2014 | Pubmed ID: 24862038
Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton.
Annals of the New York Academy of Sciences Jan, 2015 | Pubmed ID: 24961486
Erg cooperates with TGF-β to control mesenchymal differentiation.
Experimental cell research Nov, 2014 | Pubmed ID: 25139621
Chondrocyte-specific knockout of Cbfβ reveals the indispensable function of Cbfβ in chondrocyte maturation, growth plate development and trabecular bone formation in mice.
International journal of biological sciences , 2014 | Pubmed ID: 25170300
Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors.
PloS one , 2014 | Pubmed ID: 25401739
Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation.
Nature communications Mar, 2016 | Pubmed ID: 26996322
Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.
PLoS genetics 08, 2016 | Pubmed ID: 27500936
SOX9 protein is stabilized by TGF-β and regulates PAPSS2 mRNA expression in chondrocytes.
Osteoarthritis and cartilage 02, 2017 | Pubmed ID: 27746378
TGF-β regulates phosphorylation and stabilization of Sox9 protein in chondrocytes through p38 and Smad dependent mechanisms.
Scientific reports 12, 2016 | Pubmed ID: 27929080
Tgfbr2 is required in osterix expressing cells for postnatal skeletal development.
Bone 04, 2017 | Pubmed ID: 28043895
Mechanical loading regulates organization of the actin cytoskeleton and column formation in postnatal growth plate.
Molecular biology of the cell Jul, 2017 | Pubmed ID: 28539407
IVD Development: Nucleus pulposus development and sclerotome specification.
Current molecular biology reports Sep, 2018 | Pubmed ID: 30505649
Prg4 prevents osteoarthritis induced by dominant-negative interference of TGF-ß signaling in mice.
PloS one , 2019 | Pubmed ID: 30629676
Tgfbr2 is required in Acan-expressing cells for maintenance of the intervertebral and sternocostal joints.
JOR spine Jun, 2018 | Pubmed ID: 30662980
Antagonism of BMP signaling is insufficient to induce fibrous differentiation in primary sclerotome.
Experimental cell research May, 2019 | Pubmed ID: 30817928
Development of the axial skeleton and intervertebral disc.
Current topics in developmental biology , 2019 | Pubmed ID: 30902259
Scaffoldless tissue-engineered cartilage for studying transforming growth factor beta-mediated cartilage formation.
Biotechnology progress Jan, 2020 | Pubmed ID: 31461224
American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jan, 2020 | Pubmed ID: 31545883
American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies - Secondary Publication.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Jan, 2020 | Pubmed ID: 31994782