Jie Zhou

Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity.

SARS-related virus predating SARS outbreak, Hong Kong.

Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection.

A regulatory polymorphism in interferon-gamma receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection.

Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection.

Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population.

D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice.

Krüppel-like factor 15 activates hepatitis B virus gene expression and replication.

A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection.

A functional variation in CD55 increases the severity of 2009 pandemic H1N1 influenza A virus infection.

Investigation of tumor suppressing function of CACNA2D3 in esophageal squamous cell carcinoma.

Prioritizing genes responsible for host resistance to influenza using network approaches.

Surfactant protein B gene polymorphism is associated with severe influenza.

Increased expression of EIF5A2, via hypoxia or gene amplification, contributes to metastasis and angiogenesis of esophageal squamous cell carcinoma.

Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response.

Liver grafts for transplantation from donors with diabetes: an analysis of the Scientific Registry of Transplant Recipients database.

Requirement of CRTC1 coactivator for hepatitis B virus transcription.

Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9).

Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza.

Cross-protection of influenza A virus infection by a DNA aptamer targeting the PA endonuclease domain.

Receptor binding and transmission studies of H5N1 influenza virus in mammals.

Host genes and influenza pathogenesis in humans: an emerging paradigm.

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset.

Transmission of H7N9 Influenza Viruses with a Polymorphism at PB2 Residue 627 in Chickens and Ferrets.

Identification of a small-molecule inhibitor of influenza virus via disrupting the subunits interaction of the viral polymerase.

PExFInS: An Integrative Post-GWAS Explorer for Functional Indels and SNPs.

Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis.

Quantification of Influenza Virus RNA in Aerosols in Patient Rooms.

A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses.

A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.

Novel Mutations L228I and Y232H Cause Nonnucleoside Reverse Transcriptase Inhibitor Resistance in Combinational Pattern.

A novel small-molecule compound disrupts influenza A virus PB2 cap-binding and inhibits viral replication.

Novel residues in the PA protein of avian influenza H7N7 virus affect virulence in mammalian hosts.

MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2.

Isolation of H5N6, H7N9 and H9N2 avian influenza A viruses from air sampled at live poultry markets in China, 2014 and 2015.

Peptide-Mediated Interference of PB2-eIF4G1 Interaction Inhibits Influenza A Viruses' Replication in Vitro and in Vivo.

Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface.

Amino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus.

PB2 substitutions V598T/I increase the virulence of H7N9 influenza A virus in mammals.

Interplay between SIRT1 and hepatitis B virus X protein in the activation of viral transcription.

Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice.

Genetic analysis of H7N9 highly pathogenic avian influenza virus in Guangdong, China, 2016-2017.

Inhibitors of Influenza A Virus Polymerase.

Defining the sizes of airborne particles that mediate influenza transmission in ferrets.

Assessing the risk of downwind spread of avian influenza virus via airborne particles from an urban wholesale poultry market.

Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses.

Differentiated human airway organoids to assess infectivity of emerging influenza virus.

Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza.

Identification and characterization of GLDC as host susceptibility gene to severe influenza.

Establishment of a lethal aged mouse model of human respiratory syncytial virus infection.

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy.

A novel partial lid for mechanical defeatherers reduced aerosol dispersion during processing of avian influenza virus infected poultry.

Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages.

Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.

Targeting the Inositol-Requiring Enzyme-1 Pathway Efficiently Reverts Zika Virus-Induced Neurogenesis and Spermatogenesis Marker Perturbations.

Infection of bat and human intestinal organoids by SARS-CoV-2.

Attenuated Interferon and Proinflammatory Response in SARS-CoV-2-Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation.

Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients.

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study.

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target.

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters.

SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19.

Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung.

Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses.

Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies.

Development of cisplatin-loaded hydrogels for trans-portal vein chemoembolization in an orthotopic liver cancer mouse model.

STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells.

Monocytic MDSC mobilization promotes tumor recurrence after liver transplantation via CXCL10/TLR4/MMP14 signaling.

A(H1N1)pdm09 Influenza Viruses Replicating in Ferret Upper or Lower Respiratory Tract Differed in Onward Transmission Potential by Air.

Emerging SARS-CoV-2 variants expand species tropism to murines.

SPINK6 inhibits human airway serine proteases and restricts influenza virus activation.

Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron.

Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin.

A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant.

Circulating levels of periostin may help identify patients with more aggressive colorectal cancer.

Causal inference with a quantitative exposure.

Association between CD14 gene C-260T polymorphism and inflammatory bowel disease: a meta-analysis.

Association of IL-27 gene three polymorphisms with Crohn's disease susceptibility in a Chinese Han population.

Molecular design and structural optimization of potent peptide hydroxamate inhibitors to selectively target human ADAM metallopeptidase domain 17.

Safety and efficacy of sorafenib therapy in patients with hepatocellular carcinoma: final outcome from the Chinese patient subset of the GIDEON study.

Systemic delivery of IL-27 by an adeno-associated viral vector inhibits T cell-mediated colitis and induces multiple inhibitory pathways in T cells.

mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile.

Safety assessment of sorafenib in Chinese patients with unresectable hepatocellular carcinoma: subgroup analysis of the GIDEON study.

Minimally invasive spinal anesthesia for cesarean section in maternal anticoagulation therapy: a randomized controlled trial.

SUMOylation participates in induction of ischemic tolerance in mice.

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Clinical characteristics of small bowel tumors diagnosed by double-balloon endoscopy: Experience from a Chinese tertiary hospital.

Deciphering human macrophage development at single-cell resolution.

Global Burden of Bacterial Skin Diseases: A Systematic Analysis Combined With Sociodemographic Index, 1990-2019.

Burden of tuberculosis and its association with socio-economic development status in 204 countries and territories, 1990-2019.

Efficacy and safety of remimazolam tosylate for sedation during upper gastrointestinal endoscopy: study protocol for a multicenter randomized controlled trial.

The Effect of Exercise on Weight and Body Composition of Breast Cancer Patients Undergoing Chemotherapy: A Systematic Review.

Weight management personas of breast cancer patients undergoing chemotherapy in China: a multi-method study.

Correction: Weight management personas of breast cancer patients undergoing chemotherapy in China: a multi-method study.