Anil K. Rustgi

Identification of a bone marrow-derived mesenchymal progenitor cell subset that can contribute to the gastric epithelium.

K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia.

Systemic activation of K-ras rapidly induces gastric hyperplasia and metaplasia in mice.

Bile Acid and inflammation activate gastric cardia stem cells in a mouse model of barrett-like metaplasia.

Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice.

Recurrence of Esophageal Intestinal Metaplasia After Endoscopic Mucosal Resection and Radiofrequency Ablation of Barrett's Esophagus: Results From a US Multicenter Consortium.

Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research.

Fluorescent nanoparticle imaging allows noninvasive evaluation of immune cell modulation in esophageal dysplasia.

Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4.

Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.

Radiofrequency Ablation Is Associated With Decreased Neoplastic Progression in Patients With Barrett's Esophagus and Confirmed Low-Grade Dysplasia.

Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine.

Imaging of Secreted Extracellular Periostin, an Important Marker of Invasion in the Tumor Microenvironment in Esophageal Cancer.

Multiple Gastrointestinal Polyps in Patients Treated with BRAF Inhibitors.

Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia.

Our New President-Timothy C. Wang, MD.

Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis.

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus.

Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.

A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance.

Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.

Endoscopic Ultrasound Has Limited Utility in Diagnosis of Gastric Cancer in Carriers of CDH1 Mutations.

Mechanisms Underlying Metastatic Pancreatic Cancer.

Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus.

Mutant p53 on the Path to Metastasis.

Outcomes of patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study.

Loss-of-function variants in CTNNA1 detected on multigene panel testing in individuals with gastric or breast cancer.

Associations of sociodemographic and clinical factors with gastrointestinal cancer risk assessment appointment completion.

Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids.

Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma.

Our New President-M. Bishr Omary, MD, PhD, AGAF.

EMT, MET, Plasticity, and Tumor Metastasis.

Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology.

2020 American Pancreatic Association Presidential Address: Pancreatology-at the Crossroads.

The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis.

Growth of pancreatic cancers with hemizygous chromosomal 17p loss of can be preferentially targeted by PARP inhibitors.

mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression.

Potential Molecular Targets in the Setting of Chemoradiation for Esophageal Malignancies.

Rab11-FIP1 mediates epithelial-mesenchymal transition and invasion in esophageal cancer.

A clinical prediction model to assess risk for pancreatic cancer among patients with prediabetes.

PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability.

Mutant p53 regulates Survivin to foster lung metastasis.

LIN28B induces a differentiation program through CDX2 in colon cancer.

Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review.

Gene-Specific Variation in Colorectal Cancer Surveillance Strategies for Lynch Syndrome.

COVID-19 related pancreatic cancer surveillance disruptions amongst high-risk individuals.

Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence.

Emerging technologies provide insights on cancer extracellular matrix biology and therapeutics.

Extracellular ATP and Adenosine in Cancer Pathogenesis and Treatment.

Pancreatic plasticity: Unlocking exocrine lineage specification.

Stem cells and origins of cancer in the upper gastrointestinal tract.

Threshold Analysis of the Cost-effectiveness of Endoscopic Ultrasound in Patients at High Risk for Pancreatic Ductal Adenocarcinoma.

Multigene Panel Testing in Individuals With Hepatocellular Carcinoma Identifies Pathogenic Germline Variants.

Calcium signaling induces a partial EMT.

EUS-based Pancreatic Cancer Surveillance in Carriers Without a Family History of Pancreatic Cancer.

Single-cell analysis of ductal differentiation.

Diversity in Leadership at Academic Medical Centers: Addressing Underrepresentation Among Asian American Faculty.

Screening for Pancreatic Ductal Adenocarcinoma: Are We Asking the Impossible?-Letter.

Patient-derived organoids as a platform for modeling a patient's response to chemoradiotherapy in esophageal cancer.

The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.

Presentation of the Julius M. Friedenwald Medal to Timothy C. Wang, MD, AGAF.

The Multicenter Cancer of Pancreas Screening Study: Impact on Stage and Survival.

A cellular hierarchy in melanoma uncouples growth and metastasis.

Author Correction: A cellular hierarchy in melanoma uncouples growth and metastasis.

Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation.

Tumor suppressive and immune-stimulating roles of cholesterol 25-hydroxylase in pancreatic cancer cells.

KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.