Department of Internal Medicine
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The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta.
Journal of neurochemistry Dec, 2004 | Pubmed ID: 15584907
Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17015829
Transcriptional regulation of mesencephalic dopaminergic neurons: the full circle of life and death.
Movement disorders : official journal of the Movement Disorder Society Feb, 2008 | Pubmed ID: 18044702
Linkage of cDNA expression profiles of mesencephalic dopaminergic neurons to a genome-wide in situ hybridization database.
Molecular neurodegeneration , 2009 | Pubmed ID: 19178742
Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression.
Neural development , 2009 | Pubmed ID: 19291307
Transcriptional regulation of their survival: the Engrailed homeobox genes.
Advances in experimental medicine and biology , 2009 | Pubmed ID: 19731551
The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons.
Brain : a journal of neurology Jul, 2010 | Pubmed ID: 20573704
Parkinson's disease candidate gene prioritization based on expression profile of midbrain dopaminergic neurons.
Journal of biomedical science , 2010 | Pubmed ID: 20716345
Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum. Laboratory investigation.
Journal of neurosurgery Mar, 2011 | Pubmed ID: 20950087
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.
Nature cell biology Oct, 2011 | Pubmed ID: 21926988
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential.
The Journal of cell biology Oct, 2011 | Pubmed ID: 21987637
Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.
Brain research Mar, 2012 | Pubmed ID: 22364637
N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.
Nature neuroscience Apr, 2012 | Pubmed ID: 22366758
NAD kinase regulates the size of the NADPH pool and insulin secretion in pancreatic β-cells.
American journal of physiology. Endocrinology and metabolism Jul, 2012 | Pubmed ID: 22550069
A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis.
Nature cell biology Jul, 2013 | Pubmed ID: 23792689
The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed.
Journal of biomedical science , 2014 | Pubmed ID: 24685177
Bcl-xL Is Necessary for Neurite Outgrowth in Hippocampal Neurons.
Antioxidants & redox signaling Jan, 2015 | Pubmed ID: 24787232
An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2014 | Pubmed ID: 24979777
Bcl-xL in neuroprotection and plasticity.
Frontiers in physiology , 2014 | Pubmed ID: 25278904
The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole.
Molecular pharmacology Jan, 2015 | Pubmed ID: 25332381