Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in MiceEdward Cabral 1, Mary Katherine Montgomery 1, Meaghan Berg 2, Lisa Kathryn Manzuk 2, Anand Giddabasappa 1, Ziyue Karen Jiang 1
1Drug Safety R&D, Discovery & Early Development, Pfizer, Inc., 2Comparative Medicine, Discovery & Early Development, Pfizer, Inc.
This protocol describes the procedure for performing in vivo PET imaging on mice using Body Conforming Animal Molds (BCAMs) in the G8 PET/CT scanner. Technical details on mouse preparation, including proper tumor implantation, optimal positioning, BCAM-assisted PET/CT image acquisition, and data analysis, are provided.
