November 4th, 2015
•Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure.
Vidéos Connexes
5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat Video (Video) | JoVE
Echocardiographic Assessment of the Right Heart in Mice Video (Video) | JoVE
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography Video (Video) | JoVE
Assessment of Vascular Function in Patients With Chronic Kidney Disease Video (Video) | JoVE
Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets Video (Video) | JoVE
Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension Video (Video) | JoVE
A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure Video (Video) | JoVE
Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension Video (Video) | JoVE
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat Video (Video) | JoVE
Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model Video (Video) | JoVE