Results: Encapsulation of Dacarbazine Using NLC to Improve Therapeutic Profiling
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Conclusion
Transcription
The overall goal of this procedure is to prepare a nanostructured lipid carrier for encapsulating the cancer therapeutic agent dacarbazine. This procedure is simple and well-optimized. Allowing for the preparation of nanostructured lipid carrier w
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The most commonly used method for nanostructured lipid carrier (NLC) synthesis involves oil-in-water emulsion, homogenization and solidification. This was modified here by applying high shear dispersion after solidification to achieve a NLC with desirable size, improved drug encapsulation and drug loading efficiency as a potential carrier for dacarbazine delivery.