Results: Representative Effect of Fractionated Radiation on Submandibular Gland Function
6:34
Conclusion
Transcription
The overall goal of this procedure is to retroductally administer therapeutics to the submandibular glands to assess their efficacy in combating salivary disfunction. This method can help answer key questions in the field of salivary gland disorde
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Salivary gland hypofunction, a major adverse effect of head and neck radiotherapy diminishes a patient's quality of life. The demonstration of efficacy of new therapies in animal models is a prerequisite before clinical transition. This protocol describes retroductal administration and local irradiation of rat submandibular glands.