Jean-Louis Mege

Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification.

Systemic endothelial activation is greater in septic than in traumatic-hemorrhagic shock but does not correlate with endothelial activation in skin biopsies.

Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing.

IFN-gamma-induced apoptosis and microbicidal activity in monocytes harboring the intracellular bacterium Coxiella burnetii require membrane TNF and homotypic cell adherence.

Bartonella quintana bacteremia and overproduction of interleukin-10: model of bacterial persistence in homeless people.

Dysregulation of cytokines in acute Q fever: role of interleukin-10 and tumor necrosis factor in chronic evolution of Q fever.

Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3.

Whipple's disease: immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens.

Interleukin-4 induces Coxiella burnetii replication in human monocytes but not in macrophages.

Deactivation of alveolar macrophages in septic neutropenic ARDS.

Parachlamydia acanthamoebae enters and multiplies within human macrophages and induces their apoptosis [corrected].

Relationship of relapsing hip prosthesis infection by Staphylococcus aureus with gamma interferon deficiency.

Effect of sex on Coxiella burnetii infection: protective role of 17beta-estradiol.

Lipopolysaccharide from Coxiella burnetii is involved in bacterial phagocytosis, filamentous actin reorganization, and inflammatory responses through Toll-like receptor 4.

Activation and proteasomal degradation of rho GTPases by cytotoxic necrotizing factor-1 elicit a controlled inflammatory response.

Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma.

Link between impaired maturation of phagosomes and defective Coxiella burnetii killing in patients with chronic Q fever.

Ectoparasitism and vector-borne diseases in 930 homeless people from Marseilles.

Intracellular trafficking of Parachlamydia acanthamoebae.

Lack of microbicidal response in human macrophages infected with Parachlamydia acanthamoebae.

IL-16 is critical for Tropheryma whipplei replication in Whipple's disease.

Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages.

Antiangiogenic effect of erythromycin: an in vitro model of Bartonella quintana infection.

Whipple's disease: a macrophage disease.

TLR2 is necessary to inflammatory response in Coxiella burnetii infection.

Role for the CD28 molecule in the control of Coxiella burnetii infection.

CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells.

Deficient transendothelial migration of leukocytes in Q fever: the role played by interleukin-10.

Murine model of infection by Tropheryma whipplei.

The two faces of interleukin 10 in human infectious diseases.

Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection.

Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever.

A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus.

Increased levels of circulating IL-16 and apoptosis markers are related to the activity of Whipple's disease.

Coxiella burnetii infection in C57BL/6 mice aged 1 or 14 months.

Preeclampsia: impaired inflammatory response mediated by Toll-like receptors.

Infection of endothelial cells with virulent Rickettsia prowazekii increases the transmigration of leukocytes.

Persistent Coxiella burnetii infection in mice overexpressing IL-10: an efficient model for chronic Q fever pathogenesis.

Nanobacteria are mineralo fetuin complexes.

Monocyte deactivation in neutropenic acute respiratory distress syndrome patients treated with granulocyte colony-stimulating factor.

Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages.

Rickettsial diseases: from Rickettsia-arthropod relationships to pathophysiology and animal models.

The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis.

Ameobal pathogen mimivirus infects macrophages through phagocytosis.

Epidemic typhus.

Macrophage polarization in bacterial infections.

Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease.

New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis.

Intracellular life of Coxiella burnetii in macrophages.

Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis.

Adipose tissue serves as a reservoir for recrudescent Rickettsia prowazekii infection in a mouse model.

Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei.

The transcriptional programme of human heart valves reveals the natural history of infective endocarditis.

[Is macrophage polarization the Gordian knot of bacterial infections?].

Genomic, proteomic, and transcriptomic analysis of virulent and avirulent Rickettsia prowazekii reveals its adaptive mutation capabilities.

3D reconstruction of granulomas from transmitted light images implemented for long-time microscope applications.

Hijacked phagosomes and leukocyte activation: an intimate relationship.

Sex-related differences in gene expression following Coxiella burnetii infection in mice: potential role of circadian rhythm.

IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation.

Global analysis of circulating immune cells by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response.

Macrophage polarization and bacterial infections.

Circulating matrix metalloproteinases in infective endocarditis: a possible marker of the embolic risk.

Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus.

An experimental mouse model to establish Tropheryma whipplei as a diarrheal agent.

An evaluation of the effects of Lactobacillus ingluviei on body weight, the intestinal microbiome and metabolism in mice.

Effect of rickettsial toxin VapC on its eukaryotic host.

The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever.

Effects of Coxiella burnetii on MAPKinases phosphorylation.

Foxp3(+)CD4(+)CD25(+) regulatory T cells are increased in patients with Coxiella burnetii endocarditis.

The gene expression analysis of blood reveals S100A11 and AQP9 as potential biomarkers of infective endocarditis.

Defective monocyte dynamics in Q fever granuloma deficiency.

Role of innate and adaptive immunity in the control of Q fever.

Immune response and Coxiella burnetii invasion.

Cross-protection among Rickettsia species and subspecies in a guinea pig model of cutaneous infection.

Whole-cell MALDI-TOF MS: a new tool to assess the multifaceted activation of macrophages.

Overexpression of the Per2 gene in male patients with acute Q fever.

Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments.

Chronic hepatitis E virus infection is specifically associated with an interferon-related transcriptional program.

Orientia tsutsugamushi, the causative agent of scrub typhus, induces an inflammatory program in human macrophages.

Impaired stimulation of p38α-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes.

Pathogenic brucellae replicate in human trophoblasts.

Tobacco mosaic virus in the lungs of mice following intra-tracheal inoculation.

Monocyte responses in the context of Q fever: from a static polarized model to a kinetic model of activation.

Whole-cell MALDI-TOF mass spectrometry: a tool for immune cell analysis and characterization.

Placental macrophages are impaired in chorioamnionitis, an infectious pathology of the placenta.

Evaluation of Current and New Biomarkers in Severe Preeclampsia: A Microarray Approach Reveals theVSIG4 Gene as a Potential Blood Biomarker.