Christine Beeton

A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes.

Myelin basic protein-reactive T cells induce conduction failure in vivo but not in vitro.

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS.

Potassium channels as therapeutic targets for autoimmune disorders.

K+ channels as targets for specific immunomodulation.

Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.

Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins.

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases.

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.

The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily.

Potassium channels, memory T cells, and multiple sclerosis.

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.

The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation.

Discovery on Target 2007--CHI's Fifth Annual Conference. Ion channels.

Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block.

Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.

Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases.

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases.

KCa1.1 Potassium Channels Regulate Key Proinflammatory and Invasive Properties of Fibroblast-like Synoviocytes in Rheumatoid Arthritis.